Gö 6983

  • Catalog number
    9539-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    3-[1-[3-(dimethylamino)propyl]-5-methoxyindol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
  • Description
    Gö 6983 is a broad-spectrum Protein Kinase C (PKC) inhibitor; inhibits several isoforms of protein kinase C with IC₅₀ values of 7, 7, 6, 10, 60, and 20,000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ, and PKCμ, respectively). It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction.
  • CAS Number
    133053-19-7
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₆H₂₆N₄O₃
  • Molecular Weight
    442.51
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>20 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A broad-spectrum PKC inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD04040031
  • PubChem CID
    3499
  • SMILES
    CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
  • InChi
    InChI=1S/C26H26N4O3/c1-29(2)11-6-12-30-15-20(18-13-16(33-3)9-10-22(18)30)24-23(25(31)28-26(24)32)19-14-27-21-8-5-4-7-17(19)21/h4-5,7-10,13-15,27H,6,11-12H2,1-3H3,(H,28,31,32)
  • InChi Key
    LLJJDLHGZUOMQP-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    6983  
  • Short name
    Gö 6983
  • Alternative name
    Gö 6983
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