ML-7 hydrochloride

  • Catalog number
    B2000-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    Hexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepi-ne hydrochloride
  • Description
    ML-7 hydrochloride is a selective MLCK (myosin light chain kinase) inhibitor (Ki = 0.3 μM). Displays reversible, ATP-competitive inhibition of Ca²⁺-calmodulin-dependent and -independent smooth muscle MLCKs.
  • CAS Number
    110448-33-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₅H₁₇IN₂O₂S.HCl
  • Molecular Weight
    452.74
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>20 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A selective MLCK (myosin light chain kinase) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00065524
  • PubChem CID
    9803932
  • SMILES
    C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl
  • InChi
    InChI=1S/C15H17IN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H
  • InChi Key
    KDDALCDYHZIZMH-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    -7 hydrochloride
  • Alternative name
    milliliter-7 hydrochloride
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