ML-7 hydrochloride
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Catalog numberB2000-50
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PricePlease ask
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Size50 mg
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Alternative_nameHexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepi-ne hydrochloride
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DescriptionML-7 hydrochloride is a selective MLCK (myosin light chain kinase) inhibitor (Ki = 0.3 μM). Displays reversible, ATP-competitive inhibition of Ca²⁺-calmodulin-dependent and -independent smooth muscle MLCKs.
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CAS Number110448-33-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₅H₁₇IN₂O₂S.HCl
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Molecular Weight452.74
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>20 mg/ml)
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HandlingProtect from air and light
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Tag LineA selective MLCK (myosin light chain kinase) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD00065524
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PubChem CID9803932
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SMILESC1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl
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InChiInChI=1S/C15H17IN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H
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InChi KeyKDDALCDYHZIZMH-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short name-7 hydrochloride
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Alternative namemilliliter-7 hydrochloride
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