Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HOXA3
This is a highly specific antibody against HOXA3.
Homeo box 1E; Homeo box A3; Homeobox 1E; Homeobox A3; Homeobox protein HOX A3; Homeobox protein Hox-1E; Homeobox protein Hox-A3; Homeobox protein HOXA3; Homeobox1E; HomeoboxA3; HOX 1; Hox 1.5 like protein; HOX 1E; HOX A3; HOX1; Hox1.5; Hox1.5 like protein; HOX1E; HOXA 3; HOXA3; HXA3_HUMAN; MGC10155.
Purified by Protein A.
Human, Mouse, Rat
Background of the antigen
The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. HOX genes that occupy the same relative position along the 5â€™ to 3â€™ coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent HOX genes on the same chromosome. HoxA3, in conjunction with Pax1, mediates the development of the thymus, parathyroid gland, and carotid body. Its expression in the third pharyngeal arch and pouch is required for development of the third arch artery, and homozygous null HoxA3 mutants lack the carotid body. HoxA3 also regulates hindbrain development by controlling the axon projection pattern of motor neurons and sensory neurons of the proximal and distal ganglia.
1ug per 1ul
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Alternative to gene target
homeobox A3, HOX1 and HOX1E, HOXA3 and IDBG-10346 and ENSG00000105997 and 3200, HMG box domain binding, nuclei, Hoxa3 and IDBG-251785 and ENSMUSG00000079560 and 15400, HOXA3 and IDBG-633595 and ENSBTAG00000008139 and 509991