type II collagen fragment
-
Catalog numberA1096-1
-
PricePlease ask
-
Size1mg
-
-
DescriptionType II collagen is composed of a triple helix of three identical α chains. These molecules associate to form a fibril that is stabilized by intermolecular crosslinks. Type II collagen and aggrecan (a large, aggregating proteoglycan) are the two major components of the extracellular matrix of cartilage. The collagen, which is present in a fibrillar form, provides tensile strength whereas the aggrecan is responsible for compressive stiffness of cartilage.
-
FormulaC65H102N18O21
-
Molecular Weight1471.61
-
GeneCollagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
-
Gene target
-
Gene symbolCOL2A1, P4HA2, SCARB2
-
Short nameII collagen
-
IsotypeAntibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
-
Alternative nameclassification II collagen fragment
-
Gene info
-
Identity
-
Gene
-
Long gene namecollagen type II alpha 1 chain
-
Synonyms gene
-
Synonyms gene name
- collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)
- arthroophthalmopathy, progressive (Stickler syndrome)
- collagen, type II, alpha 1
- collagen type II alpha 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Collagens
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameprolyl 4-hydroxylase subunit alpha 2
-
Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II
- prolyl 4-hydroxylase, alpha polypeptide II
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-02-23
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namescavenger receptor class B member 2
-
Synonyms gene
-
Synonyms gene name
- CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1994-09-07
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Scavenger receptors
-
VEGA ID