MART-1/Melan-A, human recombinant
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Catalog number4823-1000
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PricePlease ask
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Size1 mg
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SynonymsMelanoma antigen recognized by T-cells 1, Protein Melan-A, Antigen SK29-AA, Antigen LB39-AA
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Alternative_namesMelanoma antigen recognized by T-cells 1, Protein Melan-A, Antigen SK29-AA, Antigen LB39-AA
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DescriptionA melanocyte lineage marker
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥98%
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AssaySDS-PAGE
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Purity≥98%
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Activity Specifications test methodNot available at this time
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Molecular Weight18.0 kDa
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Storage Temp-20°C
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ShippingBlue ice
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionSterile filtered and lyophilized with no additives
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Reconstitution InstructionsReconstitute in H₂O to a concentration 0.1-1 mg/ml. The solution can then be further diluted to other aqueous solutions.
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Background InformationMART-1 (also known as Melan-A) is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. SubCellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Human MART-1 is purified by proprietary chromatographic techniques.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolMLANA, RTL1, HHAT, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, SEPTIN4, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1
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Short nameMART-1/Melan-A, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameMART-1/Melan-A, H. sapiens Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namemelan-A
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Synonyms
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Locus
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Discovery year1994-08-29
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameretrotransposon Gag like 1
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Synonyms gene name
- retrotransposon-like 1
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Synonyms
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Synonyms name
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Locus
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Discovery year2006-02-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Retrotransposon Gag like
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namehedgehog acyltransferase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-09-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Membrane bound O-acyltransferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameseptin 4
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Synonyms gene
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Synonyms gene name
- peanut-like 2 (Drosophila)
- chromosome 17 open reading frame 47
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Septins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
