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KDM1A Antibody ALEXA FLUOR

KDM1A Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-3821R-A350 | KDM1A Antibody, ALEXA FLUOR 350 size: 100ul | 441.94 USD

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bs-3821R-A488 | KDM1A Antibody, ALEXA FLUOR 488 size: 100ul | 441.94 USD

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bs-3821R-A555 | KDM1A Antibody, ALEXA FLUOR 555 size: 100ul | 441.94 USD

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bs-3821R-A594 | KDM1A Antibody, ALEXA FLUOR 594 size: 100ul | 441.94 USD

Catalog number bs-3821R-A594
Price 441.94 USD
Size 100ul
Long name KDM1A Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
Also known as Anti-KDM1A PAb ALEXA FLUOR 594
Conjugated with ALEXA FLUOR® 594
Excitation emission 590nm/617nm
Properties For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
French translation anticorps
Label ALEXA FLUOR 594
Alternative name KDM1A Polyclonal Antibody, ALEXA FLUOR 594
1. Gene info
Identity 29079
Gene KDM1A
Long gene name lysine demethylase 1A
Synonyms gene
  • AOF2
  • KDM1
Synonyms gene name
  • amine oxidase (flavin containing) domain 2
  • lysine (K)-specific demethylase 1
Synonyms
  • KIAA0601
  • BHC110
  • LSD1
Synonyms name
  • Lysine-specific histone demethylase 1A
GenBank acession
  • AL031428
Locus 1p36.12
Discovery year 2004-02-26
Entrez gene record 23028
Pubmed identfication
  • 9628581
  • 12493763
RefSeq identity
  • NM_015013
Classification
  • MicroRNA protein coding host genes
  • Lysine demethylases
Havana BLAST/BLAT OTTHUMG00000003220
Product images
    #.png#bs#.jpgFormalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-KDM1 Polyclonal Antibody, Unconjugated(bs-3821R) 1:200 followed by conjugation to the secondary antibody and DAB staining
Product files

bs-3821R-A647 | KDM1A Antibody, ALEXA FLUOR 647 size: 100ul | 441.94 USD

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Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen KDM1A
Specificity This is a highly specific antibody against KDM1A.
Modification Unmodified
Modification Site None
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Immunogen range 120-170/852
Subcellular location Nucleus
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KDM1A
Gene ID Number 23028
Swiss Prot O60341
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human, Mouse, Rat
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity. Also acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and mediating demethylation of H3K9me, a specific tag for epigenetic transcriptional repression. The presence of PRKCB in ANDR-containing complexes, which mediates phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag that prevents demethylation H3K4me, prevents H3K4me demethylase activity of KDM1A. Demethylates di-methylated 'Lys-370' of p53/TP53 which prevents interaction of p53/TP53 with TP53BP1 and represses p53/TP53-mediated transcriptional activation. Demethylates and stabilizes the DNA methylase DNMT1. Required for gastrulation during embryogenesis. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Effector of SNAI1-mediated transcription repression of E-cadherin/CDH1, CDN7 and KRT8. Required for the maintenance of the silenced state of the SNAI1 target genes E-cadherin/CDH1 and CDN7.
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Synonyms AOF2; KDM1; LSD1; BHC110; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2; KDM1A; KIAA0601
Gene targetKDM1A
Short name Anti-KDM1A
Technique Antibody
Isotype Immunoglobulin G (IgG)
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Anti-KDM1A | Technique alternative | 01011199931
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