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Anti-ABI1 (Polyclonal), ALEXA Fluor 594

Anti-ABI1 (Polyclonal), ALEXA Fluor 594 is available 1 time from Bioss polyclonal antibodies labs

GENTObs-1961R-A594 | Anti-ABI1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters | 583.67 USD

Catalog number GENTObs-1961R-A594
Price 583.67 USD
Size 100 microliters
1. Gene info
Identity 11320
Gene ABI1
Long gene name abl interactor 1
Synonyms gene
  • SSH3BP1
Synonyms gene name
  • spectrin SH3 domain binding protein 1
  • abl-interactor 1
Synonyms
  • E3B1
  • ABI-1
GenBank acession
  • U87166
Locus 10p12.1
Discovery year 1999-05-17
Entrez gene record 10006
Pubmed identfication
  • 9593709
  • 9010225
RefSeq identity
  • NM_005470
Havana BLAST/BLAT OTTHUMG00000017848
Product images
    Lane 1: rat brain lysates Lane 2: rat heart lysates probed with Anti ABI1 Polyclonal Antibody, Unconjugated (bs-1961R) at 1:200 in 4?C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in 37?C. Predicted band 56kD. Observe
Type Conjugated Primary Antibody
Conjugated with ALEXA FLUOR® 594
Host organism Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide ABI1
Specificity This antibody reacts specifically with ABI1
Modification No modification has been applied to this antibody
Modification site None
Clonality Polyclonal Antibody
Clone Polyclonal Antibodies
Concentration 1ug per 1ul
Subcellular locations Cytoplasm, Nucleus
Antigen Source KLH conjugated synthetic peptide derived from human ABI1
Gene ID 10006
Swiss Prot Q8IZP0
Applications IF(IHC-P)
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.
Purification method Purified by Protein A.
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission 590nm/617nm
Synonyms E3B1; ABI-1; ABLBP4; NAP1BP; SSH3BP; SSH3BP1; Abl interactor 1; Abelson interactor 1; Abl-binding protein 4; Eps8 SH3 domain-binding protein; Eps8-binding protein; Nap1-binding protein; Spectrin SH3 domain-binding protein 1; ABI1
Also known as ABI1 Polyclonal Antibody
Other name Anti-ABI1 Polyclonal
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Gene targetABI1
Short name Anti-ABI1
Technique Polyclonal, anti
Isotype Immunoglobulin G (IgG)
Label ALEXA FLUOR 594
Alternative name ABI1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
Alternative technique polyclonals
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Anti-ABI1 | Technique alternative | 01010245291
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