5HT6 Receptor/SR-6 Antibody

• Catalog number
  bs-12058R
• Price
  Please ask
• Size
  0.1ml

• Long name
  5HT6 Receptor/SR-6 Primary Polyclonal Antibody
• Also known as
  5HT6 Receptor/SR-6 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  5HT6 Receptor/SR-6
• Specificity
  This is a highly specific antibody against 5HT6 Receptor/SR-6.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human 5HT6 Receptor/SR-6
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. Human SR-6 is one of the latest cloned receptors among the known SR receptors. ISR-6 is expressed in the limbic region, which is involved in the control of mood and emotion and in nervous system diseases such as depression and Alzheimer's disease. The cellular mechanisms of SR-6 have not been clearly elucidated.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  5 HT 6; 5 HT6; 5 hydroxytryptamine 6 receptor; 5 hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; 5-hydroxytryptamine receptor 6; 5HT 6; 5HT6R_HUMAN; HTR 6; HTR6; Serotonin receptor 6.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  5HT6   Receptor/SR-6  
• Gene symbol
  MSR1, MEGF10, MARCO, SRPRB, SIGMAR1, SNCG, CXCL16, SCAF1, ARL6IP4, SCARB2
• Short name
  Anti-5HT6 Receptor/SR-6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  5HT6 Receptor/SR-6 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7376
• Gene
  MSR1
• Long gene name
  macrophage scavenger receptor 1
• Synonyms
  • SCARA1
  • CD204
  • SR-AI
  • SR-AII
  • SR-AIII
  • SR-A
• GenBank acession
  • D13263
• Locus
  8p22
• Discovery year
  1991-08-07
• Pubmed identfication
  • 2251254
• Classification
  • CD molecules
  • Scavenger receptors
  • Scavenger receptor cysteine rich domain containing
• VEGA ID
  OTTHUMG00000094809

Gene info

• Identity
  HGNC:29634
• Gene
  MEGF10
• Long gene name
  multiple EGF like domains 10
• Synonyms gene name
  • multiple EGF-like-domains 10
• Synonyms
  • KIAA1780
  • SR-F3
• GenBank acession
  • AK021631
• Locus
  5q23.2
• Discovery year
  2006-03-31
• Entrez gene record
  84466
• Pubmed identfication
  • 11347906
  • 27170117
• RefSeq identity
  • NM_032446
• Classification
  • Scavenger receptors
• VEGA ID
  OTTHUMG00000128984

Gene info

• Identity
  HGNC:6895
• Gene
  MARCO
• Long gene name
  macrophage receptor with collagenous structure
• Synonyms
  • SCARA2
  • SR-A6
• Synonyms name
  • scavenger receptor class A, member 2
• GenBank acession
  • AF035819
• Locus
  2q14.2
• Discovery year
  1998-11-26
• Entrez gene record
  8685
• Pubmed identfication
  • 9468508
  • 7867067
  • 10331948
• RefSeq identity
  • NM_006770
• Classification
  • Scavenger receptors
  • Scavenger receptor cysteine rich domain containing
• VEGA ID
  OTTHUMG00000131400

Gene info

• Identity
  HGNC:24085
• Gene
  SRPRB
• Long gene name
  SRP receptor subunit beta
• Synonyms gene name
  • signal recognition particle receptor, B subunit
• Synonyms
  • APMCF1
  • SR-beta
• GenBank acession
  • AK075531
• Locus
  3q22.1
• Discovery year
  2004-01-29
• Entrez gene record
  58477
• Pubmed identfication
  • 7844142
  • 10859309
• VEGA ID
  OTTHUMG00000159753

Gene info

• Identity
  HGNC:8157
• Gene
  SIGMAR1
• Long gene name
  sigma non-opioid intracellular receptor 1
• Synonyms gene
  • OPRS1
• Synonyms gene name
  • opioid receptor, sigma 1
• Synonyms
  • SR-BP1
• GenBank acession
  • BC004899
• Locus
  9p13.3
• Discovery year
  1993-03-11
• Entrez gene record
  10280
• Pubmed identfication
  • 8954936
  • 9453537
• RefSeq identity
  • NM_005866
• VEGA ID
  OTTHUMG00000019829

Gene info

• Identity
  HGNC:11141
• Gene
  SNCG
• Long gene name
  synuclein gamma
• Synonyms
  • BCSG1
  • SR
  • persyn
• Synonyms name
  • synoretin
  • breast cancer-specific gene 1
  • ɣ-synuclein
• GenBank acession
  • AF044311
• Locus
  10q23.2
• Discovery year
  1998-04-07
• Entrez gene record
  6623
• Pubmed identfication
  • 9044857
  • 9700196
• VEGA ID
  OTTHUMG00000018656
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:16642
• Gene
  CXCL16
• Long gene name
  C-X-C motif chemokine ligand 16
• Synonyms gene name
  • chemokine (C-X-C motif) ligand 16
• Synonyms
  • SR-PSOX
  • CXCLG16
  • SRPSOX
• Synonyms name
  • CXC chemokine ligand 16
• GenBank acession
  • AF275260
• Locus
  17p13.2
• Discovery year
  2001-09-21
• Entrez gene record
  58191
• Pubmed identfication
  • 11017100
  • 11060282
• RefSeq identity
  • NM_022059
• Classification
  • Chemokine ligands
  • Scavenger receptors
• VEGA ID
  OTTHUMG00000090761

Gene info

• Identity
  HGNC:30403
• Gene
  SCAF1
• Long gene name
  SR-related CTD associated factor 1
• Synonyms
  • SR-A1
  • FLJ00034
• GenBank acession
  • AK024444
• Locus
  19q13.3-q13.4
• Discovery year
  2007-08-09
• Entrez gene record
  58506
• Pubmed identfication
  • 11461075
• RefSeq identity
  • NM_021228
• VEGA ID
  OTTHUMG00000183238

Gene info

• Identity
  HGNC:18076
• Gene
  ARL6IP4
• Long gene name
  ADP ribosylation factor like GTPase 6 interacting protein 4
• Synonyms gene name
  • ADP-ribosylation-like factor 6 interacting protein 4
  • ADP-ribosylation factor-like 6 interacting protein 4
• Synonyms
  • SR-25
  • SRp25
  • SFRS20
  • SRrp37
• Synonyms name
  • SRp25 nuclear protein
  • splicing factor, arginine/serine-rich 20
• GenBank acession
  • AB035384
• Locus
  12q24.31
• Discovery year
  2002-09-18
• Entrez gene record
  51329
• Pubmed identfication
  • 10708573
  • 11884129
• RefSeq identity
  • NM_018694
• VEGA ID
  OTTHUMG00000168779

Gene info

• Identity
  HGNC:1665
• Gene
  SCARB2
• Long gene name
  scavenger receptor class B member 2
• Synonyms gene
  • CD36L2
• Synonyms gene name
  • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)
• Synonyms
  • HLGP85
  • LIMPII
  • SR-BII
  • LIMP-2
• Synonyms name
  • lysosome membrane protein 2
  • lysosomal integral membrane protein II
• GenBank acession
  • D12676
• Locus
  4q21.1
• Discovery year
  1994-09-07
• Entrez gene record
  950
• Pubmed identfication
  • 1374238
• RefSeq identity
  • NM_005506
• Classification
  • Scavenger receptors
• VEGA ID
  OTTHUMG00000130099

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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