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Anti-Glucocorticoid receptor, ALEXA Fluor 594

Anti-Glucocorticoid receptor, ALEXA Fluor 594 is available 1 time from Bioss polyclonal antibodies labs

GENTObs-0252R-A594 | Anti-Glucocorticoid receptor, ALEXA Fluor 594 size: 100 microliters | 539.12 USD

Catalog number GENTObs-0252R-A594
Price 539.12 USD
Size 100 microliters
1. Gene info
Identity7978
GeneNR3C1
Synonyms gene
Synonyms gene name
  • nuclear receptor subfamily 3, group C, member 1
  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Synonyms
GenBank acession
Locus5q31.3
Discovery year2001-06-22
Pubmed identfication
Havana BLAST/BLATOTTHUMG00000129677
MeSH Data
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Type Conjugated Primary Antibody
Conjugated with ALEXA FLUOR® 594
Host organism Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide Glucocorticoid receptor
Specificity This antibody reacts specifically with Glucocorticoid receptor
Modification No modification has been applied to this antibody
Modification site None
Clonality Polyclonal Antibody
Clone Polyclonal Antibodies
Concentration 1ug per 1ul
Subcellular locations Cytoplasm, Nucleus
Antigen Source KLH conjugated synthetic peptide derived from human Glucocorticoid receptor
Gene ID 2908
Swiss Prot P04150
Applications FCM, IF(IHC-P)
Applications with corresponding dilutions FCM(1:20-100), IF(IHC-P)(1:50-200)
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.
Purification method Purified by Protein A.
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission 590nm/617nm
Synonyms GR; GCR; GRL; GCCR; GCRST; Glucocorticoid receptor; Nuclear receptor subfamily 3 group C member 1; NR3C1
Also known as Glucocorticoid receptor Antibody
Other name Anti-Glucocorticoid receptor
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Gene targetGlucocorticoid receptor
Short name Anti-Glucocorticoid receptor,
Technique anti
Label ALEXA FLUOR 594
Alternative name antibody to-Glucocorticoid receptor, ALEXA Fluor 594
Alternative technique antibodies
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