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Bub1 Antibody ALEXA FLUOR

Bub1 Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-4294R-A350 | Bub1 Antibody, ALEXA FLUOR 350 size: 100ul | 441.94 USD

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bs-4294R-A488 | Bub1 Antibody, ALEXA FLUOR 488 size: 100ul | 441.94 USD

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bs-4294R-A555 | Bub1 Antibody, ALEXA FLUOR 555 size: 100ul | 441.94 USD

Catalog number bs-4294R-A555
Price 441.94 USD
Size 100ul
Long name Bub1 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
Also known as Anti-Bub1 PAb ALEXA FLUOR 555
Conjugated with ALEXA FLUOR® 555
Excitation emission 553nm/568nm
Properties For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation Alexa Fluor,ALEXA FLUOR 555
French translation anticorps
Label ALEXA FLUOR 555
Alternative name Bub1 Polyclonal Antibody, ALEXA FLUOR 555
1. Gene info
Identity 49529
Gene BUB1P1
Long gene name BUB1 mitotic checkpoint serine/threonine kinase pseudogene 1
Locus 10q26.2
Discovery year 2014-01-08
Entrez gene record 100422363
RefSeq identity
  • NG_025548
Havana BLAST/BLAT OTTHUMG00000184638
Product images
    #.png#bs#.jpgBub1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated
Product files

bs-4294R-A594 | Bub1 Antibody, ALEXA FLUOR 594 size: 100ul | 441.94 USD

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bs-4294R-A647 | Bub1 Antibody, ALEXA FLUOR 647 size: 100ul | 441.94 USD

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Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen Bub1
Specificity This is a highly specific antibody against Bub1.
Modification Unmodified
Modification Site None
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Immunogen range 980-1030/1085
Subcellular location Nucleus
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bub1
Gene ID Number 699
Swiss Prot O43683
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human, Mouse, Rat
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Serine/threonine-protein kinase that performs 2 crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the assembly of checkpoint proteins at the kinetochore, being required for the subsequent localization of CENPF, BUB1B, CENPE and MAD2L1. Required for the kinetochore localization of PLK1. Plays an important role in defining SGOL1 localization and thereby affects sister chromatid cohesion. Acts as a substrate for anaphase-promoting complex or cyclosome (APC/C) in complex with its activator CDH1 (APC/C-Cdh1). Necessary for ensuring proper chromosome segregation and binding to BUB3 is essential for this function. Can regulate chromosome segregation in a kinetochore-independent manner. Can phosphorylate BUB3. The BUB1-BUB3 complex plays a role in the inhibition of APC/C when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1. Kinase activity is essential for inhibition of APC/CCDC20 and for chromosome alignment but does not play a major role in the spindle-assembly checkpoint activity. Mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis.
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Synonyms BUB1A; BUB1L; hBUB1; Mitotic checkpoint serine/threonine-protein kinase BUB1; BUB1
Gene targetBub1
Short name Anti-Bub1
Technique Antibody
Isotype Immunoglobulin G (IgG)
Alternative technique antibodies
Alternative to gene target budding uninhibited by benzimidazoles 1 homolog (yeast), BUB1A and BUB1L and hBUB1, BUB1 and IDBG-65670 and ENSG00000169679 and 699, transferase activity, nuclei, Bub1 and IDBG-205152 and ENSMUSG00000027379 and 12235, BUB1 and IDBG-628990 and ENSBTAG00000021181 and 514777
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