Refer to PubMed
Net weight (g)
Recommended buffer for storage
PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Representative figure legend
Immunohistochemistry analysis using Rabbit Anti-PINX1 Polyclonal Antibody (SPC-1330). Tissue: Heart Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-PINX1 Polyclonal Antibody (SPC-1330) at 1:100. The image on the right is treated with the synthesized peptide. Rabbit Anti-PINX1 Antibody used in Immunohistochemistry (IHC) on Heart Tissue (SPC-1330)
Synthesized peptide derived from internal of human PINX1.
Antibody's other name
67-11-3 protein antibody, FLJ20565 antibody, Hepatocellular carcinoma-related putative tumor suppressor antibody, Liver-related putative tumor suppressor antibody, LPTL antibody, LPTS antibody, MGC8850 antibody, OTTHUMP00000224984 antibody, OTTHUMP00000224985 antibody, OTTHUMP00000224986 antibody, OTTHUMP00000225053 antibody, OTTHUMP00000225054 antibody, PIN2 interacting protein 1 antibody, Pin2-interacting protein X1 antibody, PIN2/TERF1-interacting telomerase inhibitor 1 antibody, PINX1 antibody, PINX1_HUMAN antibody, Protein 67-11-3 antibody, TRF1-interacting protein 1 antibody
Antibody's recommended dilutions for use
IHC (1:100), ELISA (1:20000); optimal dilutions for assays should be determined by the user.
To be tested
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Total weight (kg)
PIN2/TERF1-interacting telomerase inhibitor 1, also known as PINX1, is a human gene. It mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres, inhibits telomerase activity. it may also inhibit cell proliferation and act as tumor suppressor. Over-expression of PINX1 results in decreased telomerase activity, telomere shortening, and induction of crisis. Reduction of PINX1 leads to an increase in telomerase activity and elongation of telomeres. PINX1 differs from other proteins that regulate telomere length in that it acts on telomerase while other proteins adjust telomere length without affecting telomerase activity.
Certificate of analysis
A 1:100 dilution of SPC-1330 was sufficient for detection of PINX1 in human heart tissue using Goat Anti-Rabbit IgG as the secondary antibody.
See included datasheet or contact our support service.
Antibody's full description
Rabbit Anti-Human PINX1 Polyclonal
Country of production
Antibody's purified from
Peptide Affinity Purified
See included datasheet or contact our support service
To be tested
Antibody in cell
1. Song H. et al. (2004) Biochem. Biophys. Res. Commun. (United States) 316 (4): 1116–23. 2. Soohoo, C.Y. (2010) Journal of Biological Chemistry. 3. Yoo, J.E. (2009) Journal of Molecular Biology. 4. Zhou, X.Z. (2011) Journal of Clinical Investigation.
Detects endogenous levels of total PINX1 protein.
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