Caspase-9 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-0050R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  Caspase-9 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-Caspase-9 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Caspase-9
• Specificity
  This is a highly specific antibody against Caspase-9.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  280-330/416
• Subcellular location
  Intracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Caspase-9 subunit p35
• Gene ID Number
  842
• Swiss Prot
  P55211
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Caspase-9 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• Description
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
• French translation
  anticorps

• Gene target
  Caspase-9  
• Gene symbol
  CARD9, CASP9, CARD19
• Short name
  Anti-Caspase-9
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  Caspase-9 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16391
• Gene
  CARD9
• Long gene name
  caspase recruitment domain family member 9
• Synonyms gene name
  • caspase recruitment domain family, member 9
• GenBank acession
  • AF311287
• Locus
  9q34.3
• Discovery year
  2001-08-13
• Entrez gene record
  64170
• Pubmed identfication
  • 11053425
• RefSeq identity
  • NM_052813
• Classification
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000020925
• Locus Specific Databases
  • LRG_178

Gene info

• Identity
  HGNC:1511
• Gene
  CASP9
• Long gene name
  caspase 9
• Synonyms gene name
  • caspase 9, apoptosis-related cysteine protease
  • caspase 9, apoptosis-related cysteine peptidase
• Synonyms
  • MCH6
  • ICE-LAP6
  • APAF-3
  • PPP1R56
• Synonyms name
  • protein phosphatase 1, regulatory subunit 56
• GenBank acession
  • U60521
• Locus
  1p36.21
• Discovery year
  1996-11-11
• Entrez gene record
  842
• Pubmed identfication
  • 8663294
  • 9390557
• RefSeq identity
  • NM_032996
• Classification
  • Caspases
  • Apoptosome
  • Caspase recruitment domain containing
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000002256

Gene info

• Identity
  HGNC:28148
• Gene
  CARD19
• Long gene name
  caspase recruitment domain family member 19
• Synonyms gene
  • C9orf89
• Synonyms gene name
  • chromosome 9 open reading frame 89
  • caspase recruitment domain family, member 19
• Synonyms
  • MGC11115
  • bA370F5.1
  • BinCARD
• Synonyms name
  • Bcl10-interacting protein with CARD
• GenBank acession
  • AK057716
• Locus
  9q22.31
• Discovery year
  2004-02-19
• Entrez gene record
  84270
• Pubmed identfication
  • 15637807
• RefSeq identity
  • NM_032310
• Classification
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000020243

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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