hydrogen exchanger 3 Antibody

• Catalog number
  bs-8601R
• Price
  Please ask
• Size
  0.1ml

• Long name
  hydrogen exchanger 3 Primary Polyclonal Antibody
• Also known as
  hydrogen exchanger 3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  hydrogen exchanger 3
• Specificity
  This is a highly specific antibody against hydrogen exchanger 3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NHE3
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Na+/H+ exchanger 3; NHE 3; NHE-3; NHE3; SL9A3_HUMAN; SLC9A 3; Sodium; Slc9a3; Sodium/hydrogen exchanger 3; Sodium/hydrogen exchanger, apical epithelial; Solute carrier family 9 sodium/hydrogen exchanger, isoform 3; Solute carrier family 9 sodium/hydrogen exchanger, member 3; Solute carrier family 9 member 3; MGC126718; MGC126720.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  hydrogen   exchanger  
• Gene symbol
  SLC9A3P1, SLC9A3R1, SLC9A3R2
• Short name
  Anti-hydrogen exchanger 3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  hydrogen exchanger 3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11074
• Gene
  SLC9A3P1
• Long gene name
  solute carrier family 9 member 3 pseudogene 1
• Synonyms gene
  • NHE3P
  • SLC9A3P
  • SLC9A3P4
• Synonyms gene name
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 pseudogene
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 pseudogene
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 pseudogene 1
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 pseudogene 4
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 pseudogene 4
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 pseudogene 1
• Locus
  10q11.23
• Discovery year
  1996-03-13
• Entrez gene record
  6551
• Pubmed identfication
  • 8833252
  • 8199403
• VEGA ID
  OTTHUMG00000018226

Gene info

• Identity
  HGNC:11075
• Gene
  SLC9A3R1
• Long gene name
  SLC9A3 regulator 1
• Synonyms gene name
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
• Synonyms
  • NHERF
  • EBP50
  • NHERF1
• GenBank acession
  • AF015926
• Locus
  17q25.1
• Discovery year
  1999-02-26
• Entrez gene record
  9368
• Pubmed identfication
  • 9314537
  • 9430655
• Classification
  • PDZ domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000178863

Gene info

• Identity
  HGNC:11076
• Gene
  SLC9A3R2
• Long gene name
  SLC9A3 regulator 2
• Synonyms gene name
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
• Synonyms
  • SIP-1
  • TKA-1
  • NHERF-2
  • E3KARP
• GenBank acession
  • AF004900
• Locus
  16p13.3
• Discovery year
  1999-02-26
• Entrez gene record
  9351
• Pubmed identfication
  • 9054412
  • 9671706
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000176956

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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