C1orf187 Antibody

• Catalog number
  bs-15047R
• Price
  Please ask
• Size
  0.1ml

• Long name
  C1orf187 Primary Polyclonal Antibody
• Also known as
  C1orf187 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  C1orf187
• Specificity
  This is a highly specific antibody against C1orf187.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C1orf187
• Gene ID number
  374946
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic β-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  AGPA3119; C1orf187; Chromosome 1 open reading frame 187; Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; DRAXI_HUMAN; Draxin; FLJ34999; MGC117222; Neucrin; OTTHUMP00000002262; UNQ3119.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  C1orf187  
• Gene symbol
  DRAXIN
• Short name
  Anti-C1orf187
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  C1orf187 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:25054
• Gene
  DRAXIN
• Long gene name
  dorsal inhibitory axon guidance protein
• Synonyms gene
  • C1orf187
• Synonyms gene name
  • chromosome 1 open reading frame 187
• Synonyms
  • FLJ34999
  • Neucrin
• Synonyms name
  • dorsal repulsive axon guidance protein
  • neural tissue-specific cysteine-rich protein
• GenBank acession
  • AY358750
• Locus
  1p36.22
• Discovery year
  2005-08-12
• Entrez gene record
  374946
• Pubmed identfication
  • 19150847
• RefSeq identity
  • NM_198545
• VEGA ID
  OTTHUMG00000002227

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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