GNE-317
-
Catalog numberB1716-25
-
PricePlease ask
-
Size25 mg
-
-
Alternative_nameGNE-317; GNE317; GNE 317; 5-(6-(3-methoxyoxetan-3-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine
-
DescriptionGNE-317 is a potent and selective PI3K inhibitor with potential anticancer activity.
-
CAS Number1394076-92-6
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₁₉H₂₂N₆O₃S
-
Molecular Weight414.48
-
Cell PermeableYes
-
Purity>98%
-
SolubilitiesDMSO
-
HandlingProtect from air and light
-
Tag LineA potent and selective PI3K inhibitor
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life36 months
-
PubChem CID70676303
-
SMILESCC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)C5(COC5)OC
-
InChiInChI=1S/C19H22N6O3S/c1-11-13-14(29-15(11)19(26-2)9-28-10-19)17(25-3-5-27-6-4-25)24-16(23-13)12-7-21-18(20)22-8-12/h7-8H,3-6,9-10H2,1-2H3,(H2,20,21,22)
-
InChi KeyXOZLHJMDLKDZAL-UHFFFAOYSA-N
-
MSDS AvailableYes
-
Gene target
-
Gene symbolGNE
-
Short nameGNE-317
-
Alternative nameglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase-317
-
Alternative to gene targetglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase, DMRV and GLCNE and IBM2 and NM and Uae1, GNE and IDBG-65042 and ENSG00000159921 and 10020, hydrolase activity, Cytoplasm, Gne and IDBG-143173 and ENSMUSG00000028479 and 50798, GNE and IDBG-633656 and ENSBTAG00000001142 and 782201
-
Gene info
-
Identity
-
Gene
-
Long gene nameglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
-
Synonyms gene
-
Synonyms gene name
- UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2003-11-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
-
Locus Specific Databases