CTSG is a serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.
Store at -70°C
Characterization of structure and function; Screening of inhibitors; Standard in enzymatic and immunologiacal assays
Mentioned in the data sheet
Research area interests
Diseases associated with CTSG include Papillon-Lefevre Syndrome and Cutaneous Mastocytosis. Among its related pathways are Peptide ligand-binding receptors and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics.
Cathepsin G (EC 22.214.171.124) from human neutrophils. Prepared from whole human blood, shown to be non-reactive for HbsAG, antiHCV, anti-HBc, and negative for anti-HIV1 & 2 by FDA approved tests.
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50 mM acetate buffer pH 5.5, 250 mM NaCl
Available target modification
Member of the peptidase S1 protein family
See the data sheet
For Research Use only.
CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
Cathepsin G (CTSG) (Native Protein)
Cathepsin G (cathepsin G) (Native Protein)
Alternative to gene target
cathepsin G, CATG and CG, CTSG and IDBG-4005 and ENSG00000100448 and 1511, peptidase activity, nuclei, Ctsg and IDBG-166701 and ENSMUSG00000040314 and 13035