Cathepsin G (CTSG) (Native Protein)

• Catalog number
  30 600 302
• Price
  Please ask
• Size
  25 µg

• Protein type
  Native
• Protein subtype
  EC 3.4.21.20
• Protein family
  Member of the peptidase S1 protein family
• Protein description
  CTSG is a serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.
• Research area interests
  Diseases associated with CTSG include Papillon-Lefevre Syndrome and Cutaneous Mastocytosis. Among its related pathways are Peptide ligand-binding receptors and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics.
• Package form
  liquid
• Tested applications
  Characterization of structure and function; Screening of inhibitors; Standard in enzymatic and immunologiacal assays
• Other names
  CTSG
• Peptide sequence
  MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
• Available target modification
  No
• Expression system
  Human Blood
• Product Subtype
  full length
• Active form
  Yes
• Tag
  untagged
• Contents
  50 mM acetate buffer pH 5.5, 250 mM NaCl
• Protein purity
  >95%
• Molecular weight
  29 kDa
• UniProt number
  P08311
• Gene number
  1511
• Abbreviation
  CTSG
• Full name
  cathepsin G
• Other desciption
  Cathepsin G (EC 3.4.21.20) from human neutrophils. Prepared from whole human blood, shown to be non-reactive for HbsAG, antiHCV, anti-HBc, and negative for anti-HIV1 & 2 by FDA approved tests.
• Purification
  Mentioned in the data sheet
• PubMed citations
  See the data sheet
• Warnings
  For Research Use only.
• Shipping conditions
  dry ice
• Storage condition
  Store at -70°C
• Technical datasheet
  Contact us to receive the datasheet
• Representative figure
• Other products
• Gene
  CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.

• Gene target
  Cathepsin   CTSG   Native   Protein  
• Gene symbol
  CTSG
• Short name
  Cathepsin G (CTSG) (Native Protein)
• Species
  Homo sapiens
• Alternative name
  Cathepsin G (cathepsin G) (Native Protein)
• Alternative to gene target
  cathepsin G, CATG and CG, CTSG and IDBG-4005 and ENSG00000100448 and 1511, peptidase activity, nuclei, Ctsg and IDBG-166701 and ENSMUSG00000040314 and 13035

Gene info

• Identity
  HGNC:2532
• Gene
  CTSG
• Long gene name
  cathepsin G
• Synonyms
  • CG
• GenBank acession
  • M16117
• Locus
  14q12
• Discovery year
  1990-01-22
• Entrez gene record
  1511
• Pubmed identfication
  • 2569462
• RefSeq identity
  • NM_001911
• Classification
  • Cathepsins
  • Receptor ligands
  • Granule associated serine proteases of immune defence
• VEGA ID
  OTTHUMG00000140182

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