ARP2/ARP3 Antibody, ALEXA FLUOR 555
-
Catalog numberbs-12524R-A555
-
PricePlease ask
-
Size100ul
-
-
Long nameARP2/ARP3 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
-
Also known asAnti-ARP2/ARP3 PAb ALEXA FLUOR 555
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 555
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenARP2/ARP3
-
SpecificityThis is a highly specific antibody against ARP2/ARP3.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARP2/ARP3
-
Gene ID Number10097
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenActin polymerization is required for a variety of cell functions, including chemotaxis, cell migration, cell adhesion, and platelet activation. Cells trigger actin polymerization through either the de novo nucleation of filaments from monomeric actin, the severing of existing filaments to create uncapped barbed ends, or the uncapping of existing barbed ends. The nucleation of actin is a rate-limiting and unfavorable reaction in actin polymerization and therefore requires the involvement of the Arp2/3 complex, which helps create new filaments and promotes the end-to-side cross-linking of actin filaments into the branching meshwork. The Arp2/3 complex consists of the actin-related proteins Arp2 and Arp3, and various other accessory proteins. The Arp2/3 complex promotes actin nucleation by binding the pointed end of actin filaments, or by associating with the side of an existing filament, and nucleates growth in the barbed direction. In addition, the Arp2/3 complex also mediates actin cytoskeletal outgrowths that are regulated by the Rho family of small GTPases. In response to GTP-binding Cdc42, the Arp2/3 complex binds the Cdc42 substrates, namely the WASP proteins, and initiates the formation of lamellipodia and filopodia.
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission553nm/568nm
-
SynonymsActin like protein 2; Actin related protein 2; Actin-like protein 2; ACTIN-RELATED PROTEIN 2; ACTR2; ARP2 actin related protein 2 homolog yeast; ARP2; ARP2/3 COMPLEX; ARP2_HUMAN; OTTHUMP00000159937; OTTHUMP00000202270.
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor, ALEXA FLUOR 555
-
French translationanticorps
-
Gene target
-
Gene symbolACTR3, ACTR2, APOBEC3A, ANGPTL2, AP4M1, AICDA
-
Short nameAnti-ARP2/ARP3
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 555
-
Alternative nameARP2/ARP3 Polyclonal Antibody, ALEXA FLUOR 555
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameactin related protein 3
-
Synonyms gene name
- ARP3 (actin-related protein 3, yeast) homolog
- ARP3 actin-related protein 3 homolog (yeast)
- ARP3 actin related protein 3 homolog
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-05-17
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Actin related protein 2/3 complex subunits
- Actin related proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameactin related protein 2
-
Synonyms gene name
- ARP2 (actin-related protein 2, yeast) homolog
- ARP2 actin-related protein 2 homolog (yeast)
- ARP2 actin related protein 2 homolog
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-05-17
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Actin related protein 2/3 complex subunits
- Actin related proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameapolipoprotein B mRNA editing enzyme catalytic subunit 3A
-
Synonyms gene name
- apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-12-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Apolipoprotein B mRNA editing enzyme catalytic subunits
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameangiopoietin like 2
-
Synonyms gene name
- angiopoietin-like 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-02-07
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Angiopoietin like family
- Fibrinogen C domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameadaptor related protein complex 4 subunit mu 1
-
Synonyms gene name
- adaptor related protein complex 4 mu 1 subunit
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2000-09-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Adaptor related protein complex 4
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameactivation induced cytidine deaminase
-
Synonyms gene name
- activation-induced cytidine deaminase
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-09-19
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Apolipoprotein B mRNA editing enzyme catalytic subunits
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
