anti-Retinoic Acid Receptor Antibody [763]

  • Catalog number
    50-176
  • Price
    Please ask
  • Size
    0.1 mL
  • Gene info
    Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRalpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
  • Gene names
    RAR, NR1B1, Nuclear receptor subfamily 1 group B member 1, RAR-alpha
  • Antibodie s label
    unlabelled serum
  • Purity
    Protein G purified
  • Ab raised in
    Mouse
  • Type
    Monoclonal
  • Monoclonal
    763
  • Immunoglobulin
    IgG1
  • Antigen
    Peptide corresponding to amino acid residues from the N-terminal region of human retinoic acid receptor, a-isotype.
  • Immuno application
    Western Blot
  • Antibody advice
    The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with bovine, canine and mouse tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
  • Suspention pH azide
    100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
  • Keep at
    Retinoic Acid Receptor antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
  • Works with
    Human, Mouse, Dog, Bovine
  • Omim nr
    133483
  • Ncbi nr
    P10276
  • KDa
    48
  • Vial with antibody
    in solution
  • NCBI GENE nr
    5914
  • GENE symbol
    RARA
  • Antigene name
    retinoic acid receptor, alpha
  • Source
    Homo sapiens
  • Protein nr
    P10276
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Retinoic   Acid   Receptor   [763]  
  • Short name
    anti-Retinoic Acid Receptor Antibody [763]
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toRetinoic Acid Receptor (antibody to-) [763]
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
Filters
Contact
Chat with gentaur.com employee