Lipocalin 2 Antibody, ALEXA FLUOR 594

• Catalog number
  bs-1373R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  Lipocalin 2 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-Lipocalin 2 PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Lipocalin 2
• Specificity
  This is a highly specific antibody against Lipocalin 2.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  147-166/198
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lipocalin 2
• Gene ID Number
  3934
• Swiss Prot
  P80188
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  24p3; MSFI; NGAL; Neutrophil gelatinase-associated lipocalin; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Lipocalin-2; Oncogene 24p3; Siderocalin LCN2; p25; LCN2; HNL
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  Lipocalin  
• Gene symbol
  LCN2, LCN1P2, LCN1
• Short name
  Anti-Lipocalin 2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  Lipocalin 2 Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6526
• Gene
  LCN2
• Long gene name
  lipocalin 2
• Synonyms gene name
  • lipocalin 2 (oncogene 24p3)
• Synonyms
  • NGAL
  • 24p3
• Synonyms name
  • oncogene 24p3
  • neutrophil gelatinase-associated lipocalin
  • siderocalin
• Locus
  9q34.11
• Discovery year
  1994-04-29
• Entrez gene record
  3934
• Pubmed identfication
  • 7683678
• RefSeq identity
  • NM_005564
• Classification
  • Lipocalins
• VEGA ID
  OTTHUMG00000020734

Gene info

• Identity
  HGNC:23680
• Gene
  LCN1P2
• Long gene name
  lipocalin 1 pseudogene 2
• Synonyms gene
  • LCN1L2
• Synonyms gene name
  • lipocalin 1-like 2
• Synonyms
  • bA244N20.11
• Locus
  9q34.2
• Discovery year
  2005-12-22
• Entrez gene record
  653163
• RefSeq identity
  • NG_009693
• VEGA ID
  OTTHUMG00000020863

Gene info

• Identity
  HGNC:6525
• Gene
  LCN1
• Long gene name
  lipocalin 1
• Synonyms gene name
  • lipocalin 1 (protein migrating faster than albumin, tear prealbumin)
  • lipocalin 1 (tear prealbumin)
• Synonyms
  • VEGP
  • TP
  • PMFA
  • MGC71975
  • TLC
• Synonyms name
  • Von Ebner gland protein
  • tear lipocalin
  • lipocalin 1-like 2
  • tear prealbumin
• Locus
  9q34.3
• Discovery year
  1993-05-03
• Entrez gene record
  3933
• Pubmed identfication
  • 8276406
• RefSeq identity
  • NM_002297
• Classification
  • Lipocalins
• VEGA ID
  OTTHUMG00000020908

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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