Anti-NLR Family, Pyrin Domain Containing Protein 3 (NLRP3)-Rabbit polyclonal Antibody

• Catalog number
  PAK115Mu01
• Price
  Please ask
• Size
  10ug

• Organism Species
  Mus musculus (Mouse)
• Source
  Polyclonal antibody preparation
• Purification
  Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Buffer Formulation
  0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
• Item Name
  NLR Family, Pyrin Domain Containing Protein 3
• Immunogen
  RPK115Mu01-Recombinant NLR Family, Pyrin Domain Containing Protein 3 (NLRP3)
• Image number
  3
• Species reactivity
  Human,Mouse
• Sequence of immunogen
  NLRP3 (Cys671~Trp1033)
• Aplication
  WB,IHC
• Clonality
  Rabbit polyclonal
• Concentration
  500ug/ml
• Alternative Names
  AVP; AGTAVPRL; AII; AII/AVP; C1orf7; CIAS1; CLR1.1; FCAS; FCU; MWS; NALP3; PYPAF1; Cryopyrin; Cold Induced Autoinflammatory Syndrome 1; Caterpiller-Like Receptor 1.1
• Applicable Secondary Antibody
  SAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
• Manual link
• Delivery condition
  4℃ with ice bags
• Storage instructions
  Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by Cloud Clone Corp. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cloud Clone Corp adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  NLR   Family   Pyrin   Domain   Protein   NLRP3  
• Gene symbol
  NLRP3
• Short name
  Anti-NLR Family, Pyrin Domain Protein 3 (NLRP3)-Rabbit polyclonal Antibody
• Technique
  Polyclonal, Antibody, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit, Rabbits
• Alternative name
  Antibody toNLR family, Pyrin Domain Containing Protein 3 (NLR family, pyrin domain containing 3)-production species: rabbit polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies, rabbit-anti
• Alternative to gene target
  NLR family, pyrin domain containing 3, NLRP3 and IDBG-107914 and ENSG00000162711 and 114548, peptidoglycan binding, Cytoplasm, Nlrp3 and IDBG-178924 and ENSMUSG00000032691 and 216799, NLRP3 and IDBG-645402 and ENSBTAG00000001273 and 538639

Gene info

• Identity
  HGNC:16400
• Gene
  NLRP3
• Long gene name
  NLR family pyrin domain containing 3
• Synonyms gene
  • C1orf7
  • CIAS1
  • DFNA34
• Synonyms gene name
  • cold autoinflammatory syndrome 1
  • deafness, autosomal dominant 34
• Synonyms
  • AGTAVPRL
  • AII
  • AVP
  • FCAS
  • FCU
  • NALP3
  • PYPAF1
  • MWS
  • CLR1.1
• Synonyms name
  • Cryopyrin
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
• GenBank acession
  • AF054176
• Locus
  1q44
• Discovery year
  2001-08-28
• Entrez gene record
  114548
• Pubmed identfication
  • 10741953
• RefSeq identity
  • NM_004895
• Classification
  • Pyrin domain containing
  • NLR family
• VEGA ID
  OTTHUMG00000040647
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_197

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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