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CXCR3 antibody

CXCR3 antibody is available 1 time from Fitzgerald labs

70R-30896 | CXCR3 antibody size: 100 µg | 441.36 USD

Catalog number 70R-30896
Supplier fitzgerald
Price441.36 USD
Size 100 µg
Form & Buffer Purified IgG in PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% NaN3 and 50% glycerol
1. Gene info
Identity4540
GeneCXCR3
Long gene name C-X-C motif chemokine receptor 3
Synonyms gene
Synonyms gene name
  • G protein-coupled receptor 9
  • chemokine (C-X-C motif) receptor 3
GenBank acession
LocusXq13.1
Discovery year 1994-11-01
Entrez gene record2833
Pubmed identfication
Classification
  • CD molecules
  • C-X-C motif chemokine receptors
Havana BLAST/BLATOTTHUMG00000033326
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedratio of CCR4+/CXCR3+ cells was 4.45 in chemotherapy and 0.72 in immunotherapy
lack of CXCR4 expression on plasma-cell precursors is not a limiting factor for plasma-cell homing and that the expression of CXCR3 on memory B cells
The interactions between CXCL9, CXCL10 and CXCL12 expressed in decidua and villi and CXCR3, CXCR4 expressed in CD(56)(+) decidua NK cells may influence the CD(56)(+)NK cell recruitment at the maternal-fetal interface.
migration of murine and human IFN-producing cells to CXCR3 ligands in vitro requires engagement of CXCR4 by CXCL12
congruent with the concept that inflammation plays a key role in the pathogenesis of LV dysfunction, MIG, IP10 and I-TAC add diagnostic accuracy over and beyond NT-pro BNP.
CXCR3 antagonism exerts a direct anti-glioma effect and this receptor may be a potential therapeutic target for treating human glioma.
CCR5 primarily functions as a negative regulator of the antiviral CD8+ T cell response in transgenic mice during intracerebral infection with noncytolytic lymphocytic choriomeningitis virus
These data indicate that IFN-gamma mediates the recruitment of lymphocytes into the lung via production of the chemokine CXCL10, resulting in Tc1-cell alveolitis and granuloma formation.
CXCL10/CXCR3 axis promotes gastric cancer cell invasion and migration by upregulating MMP-2 and MMP-9 production via PI3K/AKT pathway.
IP-10 does not seem to be a risk factor for Alzheimer disease, but a novel rare polymorphism has been identified, which could exert a role in susceptibility.
Product images
    #CXCR#.jpg
Category Primary Antibody
Tested for WB; ELISA
Raised in Rabbit
Product Subtype Purified Polyclonal Antibodies
Antibody Subtype Polyclonal Antibodies, Purified
Specificity CXCR3 antibody detects endogenous levels of total CXCR3 protein
Isotypes IgG
Immunogen CXCR3 antibody was raised in Rabbit using a synthesized peptide derived from internal of human CXCR3 as the immunogen
Shipping Info Blue Ice
Shipping conditions Blue Ice
Applications WB, ELISA
Research Area Signal Transduction
Concentration 1 mg/ml
Storage Store at -20 deg C in small aliquots. Avoid repeated freeze-thaw cycles
Usage Recommendations WB: 1:500-1:1000, ELISA: 1:5000
Product Type Primary Antibodies
Type of Immunogen CXCR3 antibodies were raised in Rabbit using a synthesized peptide derived from internal of human CXCR3 .
Area of research Signal Transduction
Properties If you buy Antibodies supplied by fitzgerald they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetCXCR3
Short name CXCR3 antibody
Technique Antibody
Alternative name chemokine (C-X-C motif) receptor 3 (Antibody to)
Alternative technique antibodies
Alternative to gene target chemokine (C-X-C motif) receptor 3, CD182 and CD183 and CKR-L2 and CMKAR3 and GPR9 and IP10-R and Mig-R and MigR, CXCR3 and IDBG-76333 and ENSG00000186810 and 2833, C-X-C chemokine binding, Cell surfaces, Cxcr3 and IDBG-164788 and ENSMUSG00000050232 and 12766, CXCR3 and IDBG-635748 and ENSBTAG00000014798 and 497018
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