NFKB Repressing Factor (NKRF) Polyclonal Antibody
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Catalog numberCAU21944
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PricePlease ask
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Size100 μg
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Other nameITBA4; NRF; NF-Kappa B Repressing Factor; Transcription factor NRF
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ImmunogenNKRF (Met1~Val296)
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Verified reactivityHomo sapiens (Human)
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Verified applicationsWB, ICC, IHC-P, IHC-F, ELISA
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Raised inRabbit
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ClonalityPolyclonal
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Protein numberPlease see Uniprot
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Gene numberPlease refer to GenBank
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NCBI numberPlease refer to NCBI
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PurityAffinity purified. Please contact us for more details
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Antibody s concentration200μg/ml
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Storage recommendationAliquot and store at -20°C. Minimize freezing and thawing.
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Use before1 year
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Shipping requirementsBlue ice
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Estimated production time7-11 business days
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Supplementary informationApplicable secondary antibody is available. Please inquire
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NotesFor research use only. Not for diagnostic procedures.
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PropertiesIf you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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GeneNF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translationanticorps
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Gene target
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Gene symbolNKRF, NFKB1
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Short nameNFKB Repressing Factor (NKRF) Polyclonal Antibody
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TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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LabelUnconjugated. Biotin/FITC/Cy3/Cy5 labelling is available, please inquire.
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Alternative nameNFKB Repressing Factor (NKRF) polyclonal (antibody to-)
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Alternative techniquepolyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene nameNFKB repressing factor
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Synonyms gene name
- NF-kappaB repressing factor
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-11-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G-patch domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namenuclear factor kappa B subunit 1
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Synonyms gene name
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-11-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NF-kappa B complex subunits
- Ankyrin repeat domain containing
- IPT domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data