Sapacitabine

• Catalog number
  B2002-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-(1-((2R,3S,4S,5R)-3-cyano-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)palmitamide; CS682; CYC682; CYC-682
• Description
  Sapacitabine is an orally bioavailable nucleoside analog prodrug that is potentially useful for treatment of hematologic malignancies and solid tumors. The active metabolite of sapacitabine, CNDAC (2'-C-cyano-2'-deoxy-1-β-D-arabino-pentofuranosylcytosine), displays the unique mechanism of action of causing single-strand breaks (SSBs) after incorporation into DNA, which are converted into double-strand breaks (DSBs) when cells enter a second S-phase. 
• CAS Number
  151823-14-2 
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₄₂N₄O₅ 
• Molecular Weight
  490.64
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  An anticancer agent
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  153970
• PubChem CID Link
• SMILES
  CCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)C#N
• InChi
  InChI=1S/C26H42N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-23(32)28-22-16-17-30(26(34)29-22)25-20(18-27)24(33)21(19-31)35-25/h16-17,20-21,24-25,31,33H,2-15,19H2,1H3,(H,28,29,32,34)/t20-,21+,24-,25+/m0/s1
• InChi Key
  LBGFKUUHOPIEMA-PEARBKPGSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Sapacitabine  
• Short name
  Sapacitabine
• Alternative name
  Sapacitabine

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