4-Pyridinecarboxylic acid, 2-phenylhydrazide; NSC-14613
A selective inhibitor of steroyl-CoA desaturase 1 (SCD1), the key enzyme in oleic acid biosynthesis. PluriSIn 1, induces ER stress, protein synthesis attenuation, and apoptosis in hPSCs (human pluripotent stem cells). Also prevents teratoma formation from tumorigenic undifferentiated cells.
Is it cell-permeable?
≥98% by HPLC
Is this a salt?
Protect from air and light
Maximum time for storage
DMSO (>20 mg/ml) or EtOH (>15 mg/ml)
For cells, cell lines and tissues in culture till half confluency.