Lambda light chains monoclonal antibody

  • Catalog number
    1P-505-T100
  • Price
    Please ask
  • Size
    100 assays
  • Long name
    Mouse Monoclonal Antibody against Human Lambda light chains, Clone: 4C2
  • Antigen
    Lambda light chains
  • Species reactivity
    Human (Homo sapiens)
  • Negative species reactivity
    Hamster, Goat, Guinea pig, Rabbit, Sheep
  • Clonality
    Monoclonal Antibody (Mab)
  • Clone
    4C2
  • Applications
    FC, IHC(P), IHC(F), ELISA
  • Format conjugation
    PE
  • Specificity
    The antibody 4C2 reacts with lambda light chains (22.5 kDa) of human immunoglobulin.
  • Research area
    Immunoglobulins (Human)
  • Storage buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
  • Shipping and storage
    Mouse Monoclonal Antibody against Human Lambda light chains, Clone: 4C2 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
  • Background
    Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
  • Purity
    > 95% (by SDS-PAGE)
  • Purification method
    Purified by affinity chromatography
  • References
    *Os A, Bürgler S, Ribes AP, Funderud A, Wang D, Thompson KM, Tjønnfjord GE, Bogen B, Munthe LA: Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells. Cell Rep. 2013 Aug 15;4(3):566-77.
  • Properties
    If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • French translation
    anticorps
  • Gene target
  • Short name
    Anti-Lambda light chains Mab
  • Technique
    Antibody, light, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
  • Host
    Mouse (Mus musculus)
  • Isotype
    IgG1
  • Alternative name
    Mouse Monoclonal to Lambda light chains
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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