SAG Analog (cis-isomer)

• Catalog number
  2194-1000
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  3,4-Dichloro-N-(cis-4-(methylamino)cyclohexyl)-N-(3-pyridin-4-ylbenzyl)benzo[b]thiophene-2-carboxamide; Compound 10b
• Description
  A cell-permeable, highly active, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist.
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₈H₂₇Cl₂N₃OS
• Molecular Weight
  524.5
• Cell Permeable
  Yes
• Purity
  ≥98% by NMR
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  Sonic hedgehog (Shh) signaling agonist
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24months
• SMILES
  N/A
• InChi
  N/A
• InChi Key
  N/A
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  SAG   Analog   cis-isomer  
• Gene symbol
  SAG, RNF7
• Short name
  SAG Analog (cis-isomer)
• Alternative name
  SAG Analog (cis-isomer)

Gene info

• Identity
  HGNC:10521
• Gene
  SAG
• Long gene name
  S-antigen visual arrestin
• Synonyms gene name
  • S-antigen; retina and pineal gland (arrestin)
• Synonyms
  • ARRESTIN
  • RP47
• Synonyms name
  • arrestin 1
  • rod arrestin
• Locus
  2q37.1
• Discovery year
  1989-09-19
• Entrez gene record
  6295
• Pubmed identfication
  • 2249983
• RefSeq identity
  • NM_000541
• Classification
  • Classical arrestins
• VEGA ID
  OTTHUMG00000153213
• Locus Specific Databases
  • Mutations of the Arrestin Gene

Gene info

• Identity
  HGNC:10070
• Gene
  RNF7
• Long gene name
  ring finger protein 7
• Synonyms
  • SAG
  • ROC2
  • CKBBP1
• Synonyms name
  • sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2
• GenBank acession
  • AF092878
• Locus
  3q23
• Discovery year
  1999-05-28
• Entrez gene record
  9616
• Pubmed identfication
  • 10082581
  • 10230407
• RefSeq identity
  • NM_014245
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000141305

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