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anti-Prothrombin Antibody

anti-Prothrombin Antibody is available 1 time from Biovision labs

A1114-100 | anti-Prothrombin Antibody size: Prothrombin Antibody | 407.59 USD

Catalog number A1114-100
Supplier Biovision
Price 407.59 USD
Size Prothrombin Antibody
1. Gene info
Identity 3544
Gene F7
Long gene name coagulation factor VII
Synonyms gene name
  • coagulation factor VII (serum prothrombin conversion accelerator)
Synonyms name
  • eptacog alfa
  • FVII coagulation protein
  • factor VII
Locus 13q34
Discovery year 2001-06-22
Entrez gene record 2155
Pubmed identfication
  • 3264725
  • 2511201
RefSeq identity
  • NM_000131
Classification
  • Gla domain containing
Havana BLAST/BLAT OTTHUMG00000017373
Locus Specific Databases
  • LRG_554
Product images
    #0#.jpegAnti-Prothrombin Antibody
Target of this antibody: F2
Alternative names of antibody target: Coagulation factor II
Background information: Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). Conversion to thrombin is a key step in the blood coagulation pathway and catalyzes the coagulation of fibrinogen. Clinically, cases of selective deficiency are rare, although, in cases of liver cirrhosis, prothrombin is decreased. During activation, prothrombin is cleaved at Arg271-Thr272 and at Arg320-Ser321 to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. There is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin “A” chain.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
Clone: N/A
This antibody reacts with: Human
Immunogene sequence: Human Prothrombin (Cat. No. 7684-1)
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Formulation of this antibody: In PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol
Purification method: Affinity purified rabbit IgG
This antibody has been succesfully tested for use in following methods: WB
Recommended usage: WB: 1-4 µg
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetProthrombin
Short name anti-Prothrombin Antibody
Technique Antibody, anti
Alternative name antibody to-Prothrombin (Antibody to)
Alternative technique antibodies
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anti-Prothrombin Antibody | Technique alternative | 01012194
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