Active Signal Transducer And Activator Of Transcription 3 (STAT3)

• Catalog number
  APB743Hu01-100ug
• Price
  Please ask
• Size
  100ug

• Description
  Recombinant Human Signal Transducer And Activator Of Transcription 3 expressed in: Porcine
• Specifications
  Host species: Homo sapiens (Human); Expression system: Porcine; Expression region: Ile576~Pro678; Purity: > 90%; Endotoxin level:
• Additional_information
  Uniprot ID: P40763; Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 12.9kDa; Isoelectric Point: 6.3
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Additional description
  The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  Active   Signal   Transducer   Activator   Transcription   STAT3  
• Gene symbol
  STAT3
• Short name
  Active Signal Transducer Activator Of Transcription 3 (STAT3)
• Alternative name
  functionnal Signal Transducer And Activator on Transcription 3 (signal transducer and activator on transcription 3 (acute-phase response factor))
• Alternative to gene target
  signal transducer and activator of transcription 3 (acute-phase response factor), ADMIO and APRF and HIES, STAT3 and IDBG-50702 and ENSG00000168610 and 6774, protein dimerization activity, nuclei, Stat3 and IDBG-211637 and ENSMUSG00000004040 and 20848, STAT3 and IDBG-640197 and ENSBTAG00000021523 and 101910056,508541

Gene info

• Identity
  HGNC:11364
• Gene
  STAT3
• Long gene name
  signal transducer and activator of transcription 3
• Synonyms gene name
  • signal transducer and activator of transcription 3 (acute-phase response factor)
• Synonyms
  • APRF
• GenBank acession
  • BC014482
• Locus
  17q21.2
• Discovery year
  1995-11-08
• Entrez gene record
  6774
• Pubmed identfication
  • 7512451
• RefSeq identity
  • NM_139276
  • NM_003150
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000150645
• Locus Specific Databases
  • STAT3base: Mutation registry for Hyper-IgE syndrome
  • LRG_112

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