CBX2 polyclonal antibody

• Catalog number
  6840-50
• Price
  Please ask
• Size
  50 μl

• Antibody Target
  CBX2
• Target Alternative Name
  CDCA6, M33, SRXY5
• Antibody Type
  Polyclonal
• Species Reactivities
  Mouse.
• Immunogen Sequence
  Polyclonal antibody raised in rabbit against mouse CBX2 (chromobox homolog 2) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.
• Accession
  Q14781
• Gene Id
  84733
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS with 0.05% (W/V) sodium azide.
• Purification
  Whole Anti-Sera
• Application
  ELISA.
• Positive Control
  ELISA: Peptides.
• Application And Usages
  ELISA: 1:300.
• Description
  CBX2 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodelling and modification of histones; it mediates monoubiquitination of lysine 119 on histone H2A, rendering chromatin heritably changed in its expressibility. CBX2 also is involved in sexual development, acting as an activator of NR5A1 expression.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  CBX2  
• Gene symbol
  CBX2
• Short name
  CBX2 polyclonal antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Rabbit IgG
• Alternative name
  CBX2 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:1552
• Gene
  CBX2
• Long gene name
  chromobox 2
• Synonyms gene
  • CDCA6
• Synonyms gene name
  • chromobox homolog 2 (Drosophila Pc class)
  • cell division cycle associated 6
  • chromobox homolog 2
• Synonyms
  • MGC10561
  • M33
• Synonyms name
  • Pc class homolog (Drosophila)
• GenBank acession
  • BC004252
  • BG354579
• Locus
  17q25.3
• Discovery year
  1994-05-25
• Entrez gene record
  84733
• Pubmed identfication
  • 7782071
  • 2477932
• RefSeq identity
  • NM_032647
• Classification
  • Chromobox family
• VEGA ID
  OTTHUMG00000177463

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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