CBX2 polyclonal antibody
-
Catalog number6840-50
-
PricePlease ask
-
Size50 μl
-
-
Antibody TargetCBX2
-
Target Alternative NameCDCA6, M33, SRXY5
-
Antibody TypePolyclonal
-
Species ReactivitiesMouse.
-
Immunogen SequencePolyclonal antibody raised in rabbit against mouse CBX2 (chromobox homolog 2) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.
-
AccessionQ14781
-
Gene Id84733
-
AppearanceColorless liquid
-
FormLiquid
-
FormulationIn PBS with 0.05% (W/V) sodium azide.
-
PurificationWhole Anti-Sera
-
ApplicationELISA.
-
Positive ControlELISA: Peptides.
-
Application And UsagesELISA: 1:300.
-
DescriptionCBX2 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodelling and modification of histones; it mediates monoubiquitination of lysine 119 on histone H2A, rendering chromatin heritably changed in its expressibility. CBX2 also is involved in sexual development, acting as an activator of NR5A1 expression.
-
Storage Condition-20 °C
-
Shipping Conditiongel pack
-
Shelf Life12 months
-
UsageFor Research Use Only! Not to be used in humans.
-
HandlingThe antibody solution should be gently mixed before use.
-
Western Blot VerifiedNot Verified
-
Immunocytochemistry VerifiedNot Verified
-
Immunofluorescence VerifiedNot Verified
-
Immunoprecipitation VerifiedNot Verified
-
ELISA VerifiedVerified
-
ChIP VerifiedNot Verified
-
Dot Blot VerifiedNot Verified
-
Flow Cytometry VerifiedNot Verified
-
PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
-
French translationanticorps
-
Gene target
-
Gene symbolCBX2
-
Short nameCBX2 polyclonal antibody
-
TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
IsotypeRabbit IgG
-
Alternative nameCBX2 polyclonal (antibody to-)
-
Alternative techniquepolyclonals, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namechromobox 2
-
Synonyms gene
-
Synonyms gene name
- chromobox homolog 2 (Drosophila Pc class)
- cell division cycle associated 6
- chromobox homolog 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1994-05-25
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Chromobox family
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data