Recombinant Human Autophagy Related 5 Homolog/ATG5 Protein 50µg
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Catalog numberPKSH032101-50µg
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PricePlease ask
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Size50µg
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SynonymAutophagy protein 5; APG5-like; Apoptosis-specific protein; APG5L; ASP; ATG5;
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ActivityNA
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SequenceMet1-Asp275
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Fusion tagNA
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AccessionQ9H1Y0
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Expressed HostE.coli
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ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity>90% as determined by reducing SDS-PAGE.
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Endotoxin<1.0 EU per µg as determined by LAL test.
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Stability and StorageStore at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
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Mol Mass32.4 kDa
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AP Mol Mass33 kDa
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FormulationSupplied as a 0.2 μm filtered solution of 20mM Tris,0.2M NaCl,1mM DTT,40%glycerol, pH 8.0 .
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ReconstitutionPlease refer to it for detailed information.
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BackgroundATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolATG5
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Short nameRecombinant Autophagy 5 Homolog/ATG5 Protein 50µg
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens Autophagy Related 5 Homolog/autophagy related 5 Protein 50µg
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Alternative techniquerec
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Alternative to gene targetautophagy related 5, APG5 and APG5-LIKE and APG5L and ASP and hAPG5, ATG5 and IDBG-94856 and ENSG00000057663 and 9474, protein binding, Plasma membranes, Atg5 and IDBG-148568 and ENSMUSG00000038160 and 11793, ATG5 and IDBG-631895 and ENSBTAG00000005400 and 532686
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Gene info
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Identity
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Gene
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Long gene nameautophagy related 5
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Synonyms gene
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Synonyms gene name
- APG5 (autophagy 5, S. cerevisiae)-like
- APG5 autophagy 5-like (S. cerevisiae)
- ATG5 autophagy related 5 homolog (S. cerevisiae)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-09-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Autophagy related
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data