MOUSE Anti-ATIC Antibody

  • Catalog number
    GEN214410
  • Price
    Please ask
  • Size
    100ug
  • Also known as
    ATIC
  • Other names
    bifunctional purine biosynthesis protein PURH; Bifunctional purine biosynthesis protein PURH; bifunctional purine biosynthesis protein PURH; AICARFT/IMPCHASE; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; AICAR transformylase
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    ATIC
  • Gene name synonims
    N/A
  • Other gene names
    ATIC; ATIC; PURH; AICAR; AICARFT; IMPCHASE; PURH
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG1
  • Clone
    F38 P7 H9
  • Host organism
    Mouse (Mus musculus)
  • Species reactivity
    Synthetic Peptide; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    ATIC This item specifically recognises ATIC, otherwise known as AICAR, a ribonucleotide formyltransferase (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) and member of the purH family, which helps catalyze the final steps of the purine biosynthesis pathway. _x000D__x000D_ATIC has been identified as an activator of AMP-activated protein kinase (AMPK), a known regulator of energy homeostasis, inhibitor of cell proliferation and inducer of apoptosis in cancerous cells of various origins, making ATIC a potential therapeutic agent for cancer. The anti-inflammatory and neuroprotective functions of ATIC, also have implications for its use in the treatment of Alzheimer's disease.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    N/A
  • Form Appearance
    Purified (Purified IgG - liquid)
  • Concentration
    IgG concentration 1.0mg/ml
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
  • Tested applications
    Immunohistology - Paraffin (IHC), Western Blot (WB)
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • French translation
    anticorps
  • Gene target
    ATIC  
  • Gene symbol
    ATIC
  • Short name
    MOUSE Anti-ATIC Antibody
  • Technique
    Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, mouses
  • Host
    mouse
  • Species
    Mouse, Mouses
  • Alternative name
    Anti-MOUSE ANTI ATIC
  • Alternative technique
    antibodies, murine
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee