Bovine Fibrinogen Antibody

• Catalog number
  bs-10361R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Bovine Fibrinogen Primary Polyclonal Antibody
• Also known as
  Bovine Fibrinogen PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Bovine Fibrinogen
• Specificity
  This is a highly specific antibody against Bovine Fibrinogen.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  Fibrinogen from bovine plasma
• Gene ID number
  522039
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Bovine
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  FGA; FGA protein; FGB; FGG; Fib2; Fibrin alpha chain ;Fibrinogen A alpha polypeptide; Fibrinogen A alpha polypeptide chain; Fibrinogen alpha chain; Fibrinogen B alpha polypeptide; Fibrinogen beta chain; Fibrinogen G alpha polypeptide; Fibrinogen gamma chain; MGC104327; MGC119422; MGC119423; MGC119425; MGC120405.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Fibrinogen  
• Gene symbol
  FGG, FGB, FGA
• Short name
  Anti-Bovine Fibrinogen
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Species
  Bovine, Bos Taurus genes are available form the Bovine Genome database.
• Alternative name
  Bovine Fibrinogen Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3694
• Gene
  FGG
• Long gene name
  fibrinogen gamma chain
• Synonyms gene name
  • fibrinogen, gamma polypeptide
• Locus
  4q32.1
• Discovery year
  2001-06-22
• Entrez gene record
  2266
• RefSeq identity
  • NM_021870
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000150329
• Locus Specific Databases
  • LOVD EAHAD Coagulation Factor Variant Database
  • LRG_585

Gene info

• Identity
  HGNC:3662
• Gene
  FGB
• Long gene name
  fibrinogen beta chain
• Synonyms gene name
  • fibrinogen, B beta polypeptide
• Locus
  4q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  2244
• RefSeq identity
  • NM_005141
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000150331
• Locus Specific Databases
  • LRG_558

Gene info

• Identity
  HGNC:3661
• Gene
  FGA
• Long gene name
  fibrinogen alpha chain
• Synonyms gene name
  • fibrinogen, A alpha polypeptide
• Locus
  4q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  2243
• RefSeq identity
  • NM_000508
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000150330
• Locus Specific Databases
  • LRG_557

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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