TCP1 beta Antibody / CCT2

• Catalog number
  R32477
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TCP1 beta / CCT2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (FFPE): 1-2ug/ml
• Added buffer
  Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
• Intented use
  This TCP1 beta antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P78371
• Purity
  Antigen affinity
• Description
  T-complex protein 1 subunit beta (TCP1 beta) is a protein that in humans is encoded by the CCT2 gene. The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.
• Immunogen
  Amino acids E414-C535 from the human protein were used as the immunogen for the TCP1 beta antibody.
• Storage
  Prior to reconstitution, store at 4oC. After reconstitution, the TCP1 beta antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic, membranous
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TCP1   beta   CCT2  
• Gene symbol
  CCT2, TCP1, TRR-CCT2-1
• Short name
  Anti- TCP1 beta / CCT2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TCP1 beta / CCT2
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1615
• Gene
  CCT2
• Long gene name
  chaperonin containing TCP1 subunit 2
• Synonyms gene name
  • chaperonin containing TCP1, subunit 2 (beta)
• Synonyms
  • Cctb
• GenBank acession
  • AF026293
• Locus
  12q15
• Discovery year
  1999-02-26
• Entrez gene record
  10576
• Pubmed identfication
  • 9819444
• RefSeq identity
  • NM_006431
• Classification
  • Chaperonins
• VEGA ID
  OTTHUMG00000169383

Gene info

• Identity
  HGNC:11655
• Gene
  TCP1
• Long gene name
  t-complex 1
• Synonyms
  • D6S230E
  • CCT1
  • Ccta
• GenBank acession
  • X52882
• Locus
  6q25.3
• Discovery year
  2001-06-22
• Entrez gene record
  6950
• Pubmed identfication
  • 3476253
  • 3653076
• RefSeq identity
  • NM_030752
• Classification
  • Chaperonins
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000015937

Gene info

• Identity
  HGNC:34744
• Gene
  TRR-CCT2-1
• Long gene name
  tRNA-Arg (anticodon CCT) 2-1
• Synonyms gene
  • TRNAR20
• Synonyms gene name
  • transfer RNA arginine 20 (anticodon CCU)
  • transfer RNA-Arg (CCT) 2-1
• Synonyms
  • tRNA-Arg-CCT-2-1
• GenBank acession
  • HG983606
• Locus
  17q25.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189181
• Classification
  • Cytoplasmic transfer RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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