Human CellExp™ CD87 / uPAR / PLAUR, human recombinant

  • Catalog number
    7372-100
  • Price
    Please ask
  • Size
    100 ug
  • Synonyms
    uPAR, PLAUR, CD87, MO3
  • Alternative_names
    uPAR, PLAUR, CD87, MO3
  • Description
    Acts as a receptor for urokinase plasminogen activator
  • Recombinant
    Yes
  • Source
    HEK293 cells
  • Purity by SDS PAGE
    ≥92%
  • Assay
    SDS-PAGE
  • Biological activity
    Measured by its binding ability in a functional ELISA. Immobilized human uPAR at 5 ug/ml (100 ul/well) can bind biotinylated human UPA with a linear range of 25 - 500 ng/ml.
  • Results
    Measured by its binding ability in a functional ELISA. Immobilized human uPAR at 5 ug/ml (100 ul/well) can bind biotinylated human UPA with a linear range of 25 - 500 ng/ml.
  • Molecular Weight
    This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 32.1 kDa. The predicted N-terminus is Leu 23. DTT-reduced Protein migrates as 44-48 kDa due to glycosylation.
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
  • Reconstitution Instructions
    Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
  • Background Information
    Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR act as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    CellExp™   CD87   uPAR   PLAUR  
  • Gene symbol
    PLAUR
  • Short name
    CellExp™ CD87 / uPAR / PLAUR, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ CD87 / uPAR / plasminogen activator, urokinase receptor, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    plasminogen activator, urokinase receptor, CD87 and U-PAR and UPAR and URKR, PLAUR and IDBG-55442 and ENSG00000011422 and 5329, U-plasminogen activator receptor activity, nuclei, Plaur and IDBG-154827 and ENSMUSG00000046223 and 18793, PLAUR and IDBG-639118 and ENSBTAG00000013125 and 281983
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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