Human CellExp™ CD87 / uPAR / PLAUR, human recombinant
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Catalog number
7372-100
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Price
Please ask
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Size
100 ug
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Synonyms
uPAR, PLAUR, CD87, MO3
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Alternative_names
uPAR, PLAUR, CD87, MO3
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Description
Acts as a receptor for urokinase plasminogen activator
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Recombinant
Yes
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Source
HEK293 cells
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Purity by SDS PAGE
≥92%
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Assay
SDS-PAGE
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Biological activity
Measured by its binding ability in a functional ELISA. Immobilized human uPAR at 5 ug/ml (100 ul/well) can bind biotinylated human UPA with a linear range of 25 - 500 ng/ml.
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Results
Measured by its binding ability in a functional ELISA. Immobilized human uPAR at 5 ug/ml (100 ul/well) can bind biotinylated human UPA with a linear range of 25 - 500 ng/ml.
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Molecular Weight
This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 32.1 kDa. The predicted N-terminus is Leu 23. DTT-reduced Protein migrates as 44-48 kDa due to glycosylation.
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized
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Physical form description
Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
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Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
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Background Information
Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR act as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
PLAUR
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Short name
CellExp™ CD87 / uPAR / PLAUR, recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Humans
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Alternative name
H. sapiens CellExp™ CD87 / uPAR / plasminogen activator, urokinase receptor, H. sapiens Rec.
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Alternative technique
rec
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Alternative to gene target
plasminogen activator, urokinase receptor, CD87 and U-PAR and UPAR and URKR, PLAUR and IDBG-55442 and ENSG00000011422 and 5329, U-plasminogen activator receptor activity, nuclei, Plaur and IDBG-154827 and ENSMUSG00000046223 and 18793, PLAUR and IDBG-639118 and ENSBTAG00000013125 and 281983
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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