Histone Methyltransferase (SUV39H1) Antibody

• Catalog number
  3942-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  HMT (SUV39H1)
• Target Alternative Name
  Histone-lysine N-methyltransferase, SUV39H1, Histone H3-K9 methyltransferase 1, H3-K9-HMTase 1, Full=Position-effect variegation 3-9 homolog, Suppressor of variegation 3-9 homolog 1, Su(var)3-9 homolog 1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat, drosophila
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 389 of mouse Histone Methyltransferase.
• Accession
  NP_035644.1
• Gene Id
  20937
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti-Histone transferase polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  3T3 cell lysate
• Application And Usages
  Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control.
• Description
  The histone methyltransferase KMT1A / SUV39H1 is the mammalian homologue of the Drosophila PEV modifier Su(var)3-9 protein. SUV39H1 contains the SET and chromo domains. In eukaryotic cells, SUV39H1 and the methyl-lysine binding protein HP1 interact to repress transcription at heterochromatic sites. SUV39H1 methylates histone H3 on lysine 9, which generates a binding site for HP1 proteins that plays a role in heterochromatin formation and gene silencing.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Histone   Methyltransferase   SUV39H1  
• Gene symbol
  SUV39H1
• Short name
  Histone Methyltransferase (SUV39H1) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Histone Methyltransferase (SUV39H1) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11479
• Gene
  SUV39H1
• Long gene name
  SUV39H1 histone lysine methyltransferase
• Synonyms gene
  • SUV39H
• Synonyms gene name
  • suppressor of variegation 3-9 (Drosophila) homolog 1
  • suppressor of variegation 3-9 homolog 1 (Drosophila)
  • suppressor of variegation 3-9 homolog 1
• Synonyms
  • KMT1A
• GenBank acession
  • AF019968
• Locus
  Xp11.23
• Discovery year
  1996-04-12
• Entrez gene record
  6839
• Pubmed identfication
  • 10202156
• RefSeq identity
  • NM_003173
• Classification
  • eNoSC complex
  • SET domain containing
  • Lysine methyltransferases
• VEGA ID
  OTTHUMG00000022701
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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