Cell-permeable. A potent and specific protein arginine N-methyltransferase (PRMTs) inhibitor (IC₅₀ = 8.8 μM for human PRMT1 and 3.0 μM for yeast Hmt1p ). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Also acts as a HIV-1 RT polymerase inhibitor (IC₅₀ = 5.0 μM).
Arginine N-methyltransferase inhibitor-1
Is this a salt?
Is it cell-permeable?
≥98% by NMR
DMSO or Ethanol or water
Maximum time for storage
Protect from light and moisture
For cells, cell lines and tissues in culture till half confluency.
AMI-1 for activation
AMI-1 to measure cellular activation