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Also known as
FceRI, alpha
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Other names
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; High affinity immunoglobulin epsilon receptor subunit alpha; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypeptide; high affinity immunoglobulin epsilon receptor alpha-subunit; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
FCER1A; FCER1A; FCE1A; FcERI; FCE1A; FcERI
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Gene name synonims
FCER1A; FCER1A; FCE1A; FcERI; FCE1A; FcERI
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Other gene names
FCER1A; FCER1A; FCE1A; FcERI; FCE1A; FcERI
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG2b, k
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Clone
AER-37 (CRA-1)
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human FceRIa.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Affinity Purified by immunoaffinity chromatography.
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Form Appearance
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applications
Western Blot (WB), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
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Test
A high affinity purification column was use to purify FceRI, alpha (Fc epsilon RI alpha, FCE1A, FCER1A, Immunoglobulin epsilon Receptor Subunit alpha, IgE Receptor) Antibody by MBS Monoclonals by chromatographic size exclusion.
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Description
The FceRI, alpha (Fc epsilon RI alpha, FCE1A, FCER1A, Immunoglobulin epsilon Receptor Subunit alpha, IgE Receptor) Antibody is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
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French translation
anticorps
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Gene target
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Gene symbol
FCER1A
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Short name
FceRI, alpha (Fc epsilon RI alpha, FCE1A, FCER1A, Immunoglobulin epsilon Receptor Subunit alpha, IgE Receptor) Antibody
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Technique
affinity, Antibody, IgE, FC, antibodies against human proteins, antibodies for, IgEs
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Isotype
IgE, IgE
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Alternative name
Anti-FceRI, alpha (Fc epsilon RI alpha, FCE1A, FCER1A, High Affinity Immunoglobulin epsilon Receptor Subunit alpha, IgE Receptor)
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Alternative technique
antibodies, immunoglobulin-e
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Alternative to gene target
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, FCE1A and FcERI, FCER1A and IDBG-103887 and ENSG00000179639 and 2205, IgE binding, Cell surfaces, Fcer1a and IDBG-205782 and ENSMUSG00000005339 and 14125, FCER1A and IDBG-630768 and ENSBTAG00000012887 and 506783
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