TNFRSF11A Polyclonal Antibody
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Catalog number
CAC07218
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Price
Please ask
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Size
50 μg
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Other name
no alternative name
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Immunogen
Recombinant human Tumor necrosis factor receptor superfamily member 11A protein (28-202AA)
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Verified reactivity
Human
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Verified applications
ELISA,WB
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Raised in
Rabbit
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Clonality
Polyclonal
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Protein number
Q9Y6Q6
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Gene number
Please refer to GenBank
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NCBI number
Please refer to NCBI
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Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
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Storage recommendation
Aliquot and store at -20°C. Minimize freezing and thawing.
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Use before
1 year
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Shipping requirements
Blue ice
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Estimated production time
3-7 business days
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Supplementary information
RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate na?ve T cell proliferation and to promote the survival of RANK + T cells. RANK is also expressed in a variety of tissues including skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. The RANK/RANKL interaction is important in the regulation of osteoclastogenesis and in dendritic-cell-mediated T cell immune responses. Impairments in RANK signaling have been implicated in the induction of expansile osteolysis and Paget disease of bone (PDB2). Recombinant human sRANK receptor is a 19.3 kDa polypeptide containing the TNFR homologous cysteine rich portion of the extracellular domain of RANK receptor (175 amino acid residues).
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Notes
For research use only. Not for diagnostic procedures.
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Properties
If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translation
anticorps
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Gene target
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Gene symbol
TNFRSF11A
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Short name
TNFRSF11A Polyclonal Antibody
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Technique
Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Label
Unconjugated
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Alternative name
tumor necrosis factor receptor superfamily, member 11a, NFKB activator polyclonal (antibody to-)
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Alternative technique
polyclonals, antibodies
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Alternative to gene target
tumor necrosis factor receptor superfamily, member 11a, NFKB activator, CD265 and FEO and LOH18CR1 and ODFR and OFE and OPTB7 and OSTS and PDB2 and RANK and TRANCER, TNFRSF11A and IDBG-4279 and ENSG00000141655 and 8792, metal ion binding, Cell surfaces, Tnfrsf11a and IDBG-185529 and ENSMUSG00000026321 and 21934, TNFRSF11A and IDBG-644974 and ENSBTAG00000007569 and 530884
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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