Eukaryotic Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

• Catalog number
  EPA855Mu61
• Price
  Please ask
• Size
  200ug

• Source
  Eukaryotic expression
• Predicted Molecular Mass KD
  NA
• Accurate Molecular Mass KD
  NA
• Organism species
  Mus musculus (Mouse)
• Item Name
  Receptor Activator Of Nuclear Factor Kappa B Ligand
• Alternative Names
  CD254; TNFSF11; ODF; OPGL; TRANCE; HRANKL2; SOdf; Tumor Necrosis Factor(ligand)superfamily Member 11; TNF-related activation-induced cytokine
• Research Area
  Signal transduction;Metabolic pathway;Apoptosis;Tumor immunity;Bone metabolism;
• Buffer Formulation
  PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Purity
  > 95%
• Protein length
  Arg72~Asp316
• Tag
  N-terminal His Tag
• Expression System
  Eukaryotic expression
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Eukaryotic   Receptor   Activator   Factor   Kappa   Ligand   RANkL  
• Short name
  Eukaryotic Receptor Activator Of Factor Kappa B Ligand (RANkL)
• Host
  293F cell
• Species
  Mus musculus (Mouse)
• Alternative name
  Eukaryotic Receptor Activator on Nuclear Factor Kappa B Ligand (RANkL)

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