ALK antibody

  • Catalog number
    3355-30T
  • Price
    Please ask
  • Size
    30 µg
  • Antibody Target
    ALK
  • Target Alternative Name
    ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human
  • Immunogen Sequence
    Synthetic peptide corresponding to C-terminus of human ALK
  • Accession
    Q9UM73
  • Gene Id
    238
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    0.5 mg/ml affinity purified rabbit anti-ALK polyclonal antibody in PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin
  • Purification
    Affinity purified
  • Application
    Western blot
  • Positive Control
    Jurkat cell lysate
  • Application And Usages
    Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
  • Description
    ALK (anaplastic lymphoma kinase) was originally discovered as a NPM (Nucleophosmin)-ALK fusion protein. The NPM-ALK is a constitutively active oncogenic tyrosine kinase associated with anaplastic lymphoma. Activation of PLCgamma by NPM-ALK has been sμggested as a crucial step for this lymphoma-associated oncogenic tyrosine kinase.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    ALK  
  • Gene symbol
    ALK, ENPP7, TGFBR1, BMPR2
  • Short name
    ALK antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    anaplastic lymphoma receptor tyrosine kinase (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    anaplastic lymphoma receptor tyrosine kinase, CD246 and NBLST3, ALK and IDBG-42084 and ENSG00000171094 and 238, transferase activity, Plasma membranes, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642
Gene info
  • Identity
  • Gene
    ALK
  • Long gene name
    ALK receptor tyrosine kinase
  • Synonyms gene name
    • anaplastic lymphoma kinase (Ki-1)
    • anaplastic lymphoma receptor tyrosine kinase
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1993-08-24
  • Entrez gene record
    238
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Receptor tyrosine kinases
    • CD molecules
  • VEGA ID
  • Locus Specific Databases
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    bone morphogenetic protein receptor type 2
  • Synonyms gene
  • Synonyms gene name
    • primary pulmonary hypertension 1
    • bone morphogenetic protein receptor, type II (serine/threonine kinase)
    • bone morphogenetic protein receptor type II
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1997-03-19
  • Entrez gene record
    659
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Type 2 receptor serine/threonine kinases
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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