Smo agonist, SAG dihydrochloride

  • Catalog number
    2801-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    N-Methyl-N′-(3-pyridinylbenzyl)-N′-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane, dihydrochloride
  • Description
    SAG hydrochloride is the water-soluble analog of SAG (Cat. No.1939). A cell-permeable Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.
  • CAS Number
    364590-63-6
  • Structure Available
    Y
  • Salt Form
    No
  • Molecular Formula
    C₂₈H₂₈ClN₃OS. 2HCl
  • Molecular Weight
    562.98
  • Cell Permeable
    Y
  • Purity
    ≥98% by HPLC
  • Solubilities
    H2O (~ 25 mg/ml) DMSO (~ 10 mg/ml)
  • Handling
    Protect from light and moisture
  • Tag Line
    A cell-permeable Smoothened (Smo) agonist
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    71433770
  • SMILES
    CNC1CCC(CC1)N(CC2=CC=CC(=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl.O.Cl.Cl
  • InChi
    InChI=1S/C28H28ClN3OS.2ClH.H2O/c1-30-22-9-11-23(12-10-22)32(28(33)27-26(29)24-7-2-3-8-25(24)34-27)18-19-5-4-6-21(17-19)20-13-15-31-16-14-20;;;/h2-8,13-17,22-23,30H,9-12,18H2,1H3;2*1H;1H2
  • InChi Key
    IYXUQUYRWPGIQL-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Gene symbol
    SAG, RNF7
  • Short name
    Smo agonist, SAG dihydrochloride
  • Alternative name
    smoothened, frizzled family receptor agonist, SAG dihydrochloride
  • Alternative to gene target
    smoothened, frizzled family receptor, FZD11 and Gx and SMOH, SMO and IDBG-40669 and ENSG00000128602 and 6608, Wnt-activated receptor activity, Cell surfaces, Smo and IDBG-132261 and ENSMUSG00000001761 and 319757, SMO and IDBG-635317 and ENSBTAG00000013287 and 539308
Gene info
Gene info
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee