anti-TNIK Antibody

• Catalog number
  48-330
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when overexpressed in Phoenix-A cells, and this activation is mediated solely by the C-terminal germinal center kinase homology region. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. At least eight splice isoforms have been reported.
• Gene names
  TNIK, ZC2, KIAA0551
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Antigen
  TNIK antibody was made against a peptide located near the internal domain of TNIK (Human).
• Immuno application
  ELISA, immuno-histo-chemistry
• Antibody advice
  TNIK antibody can be used in immunohistochemistry starting at 15 - 20 ug/mL.
• Suspention pH azide
  PBS, 0.1% sodium azide.
• Keep at
  TNIK antibody should be stored long term (months) at -80 grades C and short term (days) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Bat, Gibbon, Gorilla, Human, Monkey, Rabbit
• Omim nr
  29840818
• Ncbi nr
  Q9UKE5
• Vial with antibody
  in solution
• NCBI GENE nr
  23043
• GENE symbol
  TNIK
• Antigene name
  TRAF2 and NCK interacting kinase
• Source
  Homo sapiens
• Protein nr
  Q9UKE5
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TNIK  
• Gene symbol
  TNIK
• Short name
  anti-TNIK Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTNIK (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  TRAF2 and NCK interacting kinase, TNIK and IDBG-64741 and ENSG00000154310 and 23043, transferase activity, nuclei, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627

Gene info

• Identity
  HGNC:30765
• Gene
  TNIK
• Long gene name
  TRAF2 and NCK interacting kinase
• Synonyms
  • KIAA0551
• GenBank acession
  • AF172264
• Locus
  3q26.2-q26.31
• Discovery year
  2004-02-26
• Entrez gene record
  23043
• Pubmed identfication
  • 9628581
  • 10521462
• RefSeq identity
  • NM_015028
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000159036

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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