Human CASP1 (Caspase 1) CLIA Kit

• Catalog number
  E-CL-H0016-96T
• Price
  Please ask
• Size
  96Test

• Detection Type
  Colormetric
• Target Species
  Human
• Target Synonym
  ICE, IL1BC, P45, Interleukin 1 Beta Converting Enzyme, Apoptosis-Related Cysteine Peptidase
• Test principle
  This CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human CASP1 . Standards or samples are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human CASP1 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human CASP1 , biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of Human CASP1 . You can calculate the concentration of Human CASP1 in the samples by comparing the RLU value of the samples to the standard curve.
• Sensitivity
  3.75pg/mL
• Detection Range
  6.25~400pg/mL
• Target Name
  CASP1
• UNIProt ID
  NA
• Tested Sample Types
  Serum, Plasma, Cell supernatant
• Product Name
  Human CASP1 (Caspase 1) CLIA Kit
• Type
  Sandwich
• Technical data
• Standard Curve RUL
• Description
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  CASP1   Caspase   CLIA   Kit  
• Gene symbol
  CASP1
• Short name
  CASP1 (Caspase 1) CLIA Kit
• Species
  Human, Humans
• Alternative name
  H. sapiens caspase 1, apoptosis-related cysteine peptidase (caspase 1) CLIA reagent
• Alternative technique
  kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

Gene info

• Identity
  HGNC:1499
• Gene
  CASP1
• Long gene name
  caspase 1
• Synonyms gene
  • IL1BC
• Synonyms gene name
  • caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • caspase 1, apoptosis-related cysteine peptidase
• Synonyms
  • ICE
• Synonyms name
  • caspase-1
  • interleukin 1, beta, convertase
• GenBank acession
  • U13697
• Locus
  11q22.3
• Discovery year
  1992-05-07
• Entrez gene record
  834
• Pubmed identfication
  • 1373520
  • 9250871
• RefSeq identity
  • NM_033292
• Classification
  • Caspases
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000048072

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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