N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide;GF120918; GG 918; GW0918; GF-120918)
Elacridar is a potent P-glycoprotein (P-gp/ABCG1) and breast cancer resistance protein (BCRP) inhibitor . GF120918 increases the bioavailability of cytotoxic anti-tumor drugs, and also leads to increased levels of anti-HIV drugs in the brain and CNS.
Is it cell-permeable?
≥98% by HPLC
Is this a salt?
Protect from air and light
Maximum time for storage
DMSO (~ 2 mg/ml)
For cells, cell lines and tissues in culture till half confluency.