Human CellExp™ CD360 / IL21R, human recombinant

• Catalog number
  7373-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  IL21R, CD360, NILR
• Alternative_names
  IL21R, CD360, NILR
• Description
  Important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells
• Recombinant
  Yes
• Source
  HEK293 cells
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Biological activity
  Measured by its ability to bind human IL-21 in a functional ELISA.
• Results
  Measured by its ability to bind human IL-21 in a functional ELISA.
• Molecular Weight
  This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 25.8 kDa. The predicted N-terminus is Cys 20. DTT-reduced Protein migrates as 42-50 kDa due to glycosylation.
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
• Background Information
  Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   CD360   IL21R  
• Gene symbol
  IL21R, IL21R-AS1
• Short name
  CellExp™ CD360 / IL21R, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ CD360 / interleukin 21 receptor, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  interleukin 21 receptor, IL21R and IDBG-21873 and ENSG00000103522 and 50615, protein binding, Plasma membranes, Il21r and IDBG-209298 and ENSMUSG00000030745 and 60504, IL21R and IDBG-638787 and ENSBTAG00000019567 and 617967

Gene info

• Identity
  HGNC:6006
• Gene
  IL21R
• Long gene name
  interleukin 21 receptor
• Synonyms
  • CD360
• GenBank acession
  • AF254067
• Locus
  16p12.1
• Discovery year
  2000-03-29
• Entrez gene record
  50615
• Pubmed identfication
  • 11081504
• RefSeq identity
  • NM_181078
• Classification
  • Interleukin receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000131675
• Locus Specific Databases
  • LRG_731

Gene info

• Identity
  HGNC:27551
• Gene
  IL21R-AS1
• Long gene name
  IL21R antisense RNA 1
• Synonyms gene name
  • IL21R antisense RNA 1 (non-protein coding)
• GenBank acession
  • AK093371
• Locus
  16p12.1
• Discovery year
  2012-06-22
• Entrez gene record
  283888
• Pubmed identfication
  • 26857419
• RefSeq identity
  • NR_037158
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000176806

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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