Human CellExp™ CD360 / IL21R, human recombinant
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Catalog number
7373-100
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Price
Please ask
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Size
100 ug
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Synonyms
IL21R, CD360, NILR
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Alternative_names
IL21R, CD360, NILR
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Description
Important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells
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Recombinant
Yes
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Source
HEK293 cells
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Biological activity
Measured by its ability to bind human IL-21 in a functional ELISA.
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Results
Measured by its ability to bind human IL-21 in a functional ELISA.
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Molecular Weight
This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 25.8 kDa. The predicted N-terminus is Cys 20. DTT-reduced Protein migrates as 42-50 kDa due to glycosylation.
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized
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Physical form description
Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
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Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
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Background Information
Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
IL21R, IL21R-AS1
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Short name
CellExp™ CD360 / IL21R, recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Humans
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Alternative name
H. sapiens CellExp™ CD360 / interleukin 21 receptor, H. sapiens Rec.
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Alternative technique
rec
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Alternative to gene target
interleukin 21 receptor, IL21R and IDBG-21873 and ENSG00000103522 and 50615, protein binding, Plasma membranes, Il21r and IDBG-209298 and ENSMUSG00000030745 and 60504, IL21R and IDBG-638787 and ENSBTAG00000019567 and 617967
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Gene info
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Identity
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Gene
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Long gene name
interleukin 21 receptor
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-03-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukin receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
IL21R antisense RNA 1
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Synonyms gene name
- IL21R antisense RNA 1 (non-protein coding)
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GenBank acession
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Locus
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Discovery year
2012-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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