Mouse Monoclonal IgG1 Anti-human CD45 (LCA) [2B11/PD7/26]
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Catalog numberCD45-5
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PricePlease ask
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Size5 ml
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AvailabilityPlease contact us to check the availability
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ImmunogenActivated and neoblastic T-cells
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SpecificityCell membrane of lymphoid cells (macrophages and polymorph nuclear lymphocytes stain weakly, while plasma cells usually are negative). No reactivity with non-hematopoetic cells, epithelia and connective tissue.
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Species reactivityHuman
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Product presentationAntibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for at least 50 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. Gentaur Art. No. PU002, if further dilution is required.
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Product categoryPrimary Antibody
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Antibody s raised inMouse
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Antibody s isotypeIgG1
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Antibody s clone2B11/PD7/26
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Product is supplied asready to use
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Recommended concentration for useneat
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Protein concentrationN/A
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Positive controlTonsil
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PretreatmentNo pre-treatment with proteases necessary, improved staining with unmasking fluid G (Art. No. DE007)
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Tested applicationsIHC(P)
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Recommended secondary reagentWe recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art.-No. AE005), if higher sensitivity is required VECTASTAIN Elite ABC (Art. No. PK-6102) or ABC AP (Art. No. AK-5002) systems are applicable.
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Storage methodStore at 2-8°C
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UniProt numberGo to UniProt/SwissProt
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Litterature1. Dalchau R., Kirkley J., and Fabre J.W. (1980) Monoclonal antibody to a human leukocyte-specific membrane glykoprotein probably homologous to the leukocyte-common (L-C) antigen of the rat. Europ. J. Immunol. 10; 737-744. 2. Streuli M., Morimoto C., Schrieber M., Schlossman S.F., and Saito H. (1988) Characterization of CD45 and CD45R monoclonal antibodies using transfected mouse cell lines that express individual human leukozyte common antigens. J. Immunology 141; 3910-3914 3. Pulido R., Cebrian M., Acevedo A., De Landazuri M.O., Sanchez-Madrid F. (1988) Comparative biochemical and tissue distribution study of four distinct CD45 antigen specificities. J. Immunol. 140; 3851-3857.
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Tips*Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Testbio logo supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Latin nameMus musculus
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Gene target
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Gene symbolPTPRC, CLTA, PTPRCAP, GUCY2D
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Short nameBioprime
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TechniqueMouse monoclonal, anti-Human, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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IsotypeIgG1
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SpeciesHuman, Humans, Mouses
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Alternative nameCD45, LCA, human
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Alternative techniquemurine, antibodies
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Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase receptor type C
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein tyrosine phosphatases receptor type
- Fibronectin type III domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameclathrin light chain A
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Synonyms gene name
- clathrin, light polypeptide (Lca)
- clathrin, light chain A
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Synonyms
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Locus
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Discovery year1991-08-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Clathrin subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase receptor type C associated protein
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Synonyms
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Locus
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Discovery year1996-04-22
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Entrez gene record
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameguanylate cyclase 2D, retinal
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Synonyms gene
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Synonyms gene name
- cone rod dystrophy 6
- guanylate cyclase 2D, membrane (retina-specific)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-11-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Guanylate cyclase receptors
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VEGA ID
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Locus Specific Databases
