SNAI1 Polyclonal Antibody

• Catalog number
  CAC07269
• Price
  Please ask
• Size
  100 μg

• Other name
  Zinc finger protein SNAI1,SNAI1,SNAH,Protein snail homolog 1,Protein sna
• Immunogen
  Recombinant human Zinc finger protein SNAI1 protein (1-264AA)
• Verified reactivity
  Human
• Verified applications
  ELISA,IHC. Recommended dilution:IHC:1:20-1:200
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  O95863
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Caprylic Acid Ammonium Sulfate Precipitation Purified
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  SNAI1  
• Gene symbol
  SNAI1
• Short name
  SNAI1 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  snail homolog 1 (Drosophila) polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  snail homolog 1 (Drosophila), dJ710H13.1 and SLUGH2 and SNA and SNAH and SNAIL and SNAIL1, SNAI1 and IDBG-80676 and ENSG00000124216 and 6615, metal ion binding, nuclei, Snai1 and IDBG-213071 and ENSMUSG00000042821 and 20613, BT.61987 and IDBG-643208 and ENSBTAG00000014554 and 504492

Gene info

• Identity
  HGNC:11128
• Gene
  SNAI1
• Long gene name
  snail family transcriptional repressor 1
• Synonyms gene name
  • snail 1 (drosophila homolog), zinc finger protein
  • snail homolog 1 (Drosophila)
  • snail family zinc finger 1
• Synonyms
  • SNA
  • SLUGH2
  • SNAH
  • SNAIL1
  • SNAIL
• GenBank acession
  • AF125377
• Locus
  20q13.13
• Discovery year
  1998-07-03
• Entrez gene record
  6615
• Pubmed identfication
  • 10585766
• Classification
  • Zinc fingers C2H2-type
  • SNAG transcriptional repressors
• VEGA ID
  OTTHUMG00000033048

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products