CASK/CAMGUK Antibody

• Catalog number
  bs-11338R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CASK/CAMGUK Primary Polyclonal Antibody
• Also known as
  CASK/CAMGUK PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CASK/CAMGUK
• Specificity
  This is a highly specific antibody against CASK/CAMGUK.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CASK
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling. CASK (also designated LIN-2) belongs to a MAGUK subfamily which is characterized by a novel domain structure that consists of a calcium/calmodulin- dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is expressed in rat brain where it binds to cell-surface proteins, such as neurexin and syndecan, and is thought to be involved in signaling at neuronal synapses. CASK translocates to the nucleus and interacts with Tbr-1 to form a complex, which binds to a specific DNA sequence (the T-element), and induces the expression of specific genes, including Reelin. CASK displays a transcription regulation function, which appears crucial for cerebrocortical development.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CAGH39; Caki; Calcium/calmodulin dependent serine protein kinase; Calcium/calmodulin dependent serine protein kinase MAGUK family; Calcium/calmodulin dependent serine protein kinase membrane associated guanylate kinase; Calcium/calmodulin-dependent serine protein kinase; CAMGUK; CAMGUK protein; CAMGUK, drosophila, homolog of antibody casK; CMG; CSKP_HUMAN; DXPri1; DXRib1; FGS4; hCASK; LIN 2; Lin 2 homolog; LIN2 antibody Lin2 homolog; MICPCH; MRXSNA; Pals3; Peripheral plasma membrane protein CASK; Protein lin-2 homolog; TNRC8; Trinucleotide repeat containing 8; Vertebtate LIN2 homolog.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CASK/CAMGUK  
• Gene symbol
  CASK-AS1, CASK
• Short name
  Anti-CASK/CAMGUK
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CASK/CAMGUK Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  calcium/calmodulin-dependent serine protein kinase (MAGUK family), CAGH39 and CAMGUK and CMG and FGS4 and LIN2 and MICPCH and MRXSNA and TNRC8, CASK and IDBG-57627 and ENSG00000147044 and 8573, transferase activity, nuclei, Cask and IDBG-133241 and ENSMUSG00000031012 and 12361, CASK and IDBG-637908 and ENSBTAG00000020136 and 404149

Gene info

• Identity
  HGNC:40126
• Gene
  CASK-AS1
• Long gene name
  CASK antisense RNA 1
• Synonyms gene name
  • CASK antisense RNA 1 (non-protein coding)
• Locus
  Xp11.4
• Discovery year
  2011-07-29
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000021372

Gene info

• Identity
  HGNC:1497
• Gene
  CASK
• Long gene name
  calcium/calmodulin dependent serine protein kinase
• Synonyms gene
  • TNRC8
• Synonyms gene name
  • trinucleotide repeat containing 8
  • calcium/calmodulin-dependent serine protein kinase (MAGUK family)
• Synonyms
  • LIN2
  • CAGH39
  • FGS4
• GenBank acession
  • AF035582
• Locus
  Xp11.4
• Discovery year
  1998-09-25
• Entrez gene record
  8573
• Pubmed identfication
  • 9722958
• RefSeq identity
  • NM_003688
• Classification
  • Membrane associated guanylate kinases
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000021378
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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